Cargando…

Downregulation of Uncoupling Protein 2(UCP2) Mediated by MicroRNA-762 Confers Cardioprotection and Participates in the Regulation of Dynamic Mitochondrial Homeostasis of Dynamin Related Protein1 (DRP1) After Myocardial Infarction in Mice

Acute myocardial infarction (MI) is one of the leading causes of death in the world, and its pathophysiological mechanisms have not been fully elucidated. The purpose of this study was to investigate the role and mechanism of uncoupling protein 2 (UCP2) after MI in mouse heart. Here, we examined the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Dehui, Zou, Shangrong, Li, Guangnan, Zhang, Qiyu, Chen, Chunlin, Li, Cuizhi, Song, Huafeng, Chen, Shaoxian, Wang, Jiawen, Wu, Yueheng, Liu, Youbin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907155/ https://www.ncbi.nlm.nih.gov/pubmed/35284500 http://dx.doi.org/10.3389/fcvm.2021.764064

Ejemplares similares

LncRNA PVT1 Knockdown Ameliorates Myocardial Ischemia Reperfusion Damage via Suppressing Gasdermin D-Mediated Pyroptosis in Cardiomyocytes
por: Li, Cuizhi, et al.
Publicado: (2021)

Integrated Strategies of Diverse Feature Selection Methods Identify Aging-Based Reliable Gene Signatures for Ischemic Cardiomyopathy
por: Song, Huafeng, et al.
Publicado: (2022)

New Aspects of Mitochondrial Uncoupling Proteins (UCPs) and Their Roles in Tumorigenesis
por: Robbins, Delira, et al.
Publicado: (2011)

Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases
por: Pravednikova, Anna E., et al.
Publicado: (2020)

Relationships between Uncoupling Protein Genes UCP1, UCP2 and UCP3 and Irisin Levels in Residents of the Coldest Region of Siberia
por: Nikanorova, Alena A., et al.
Publicado: (2022)

Unveiling the Role of the Proton Gateway, Uncoupling Proteins (UCPs), in Cancer Cachexia
por: Joshi, Mit, et al.
Publicado: (2023)

Prognostic impact of Dynamin related protein 1 (Drp1) in epithelial ovarian cancer
por: Tsuyoshi, Hideaki, et al.
Publicado: (2020)

Mitochondrial Dynamin-Related Protein Drp1: a New Player in Cardio-oncology
por: Deng, Yali, et al.
Publicado: (2022)

Interaction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteins
por: Ortiz-Sandoval, Carolina G, et al.
Publicado: (2014)

Novel roles for Arabidopsis dynamin-related proteins DRP1A and DRP2B in resistance against Botrytis cinerea fungal infection
por: Mc Gowan, Grant, et al.
Publicado: (2022)

Expressions of mRNA and encoded proteins of mitochondrial uncoupling protein genes (UCP1, UCP2, and UCP3) in epicardial and mediastinal adipose tissue and associations with coronary artery disease
por: Huesca-Gómez, Claudia, et al.
Publicado: (2023)

Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis
por: Wang, Ping, et al.
Publicado: (2015)

Physiological and Pathological Significance of Dynamin-Related Protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System
por: Cho, Bongki, et al.
Publicado: (2013)

Molecular determinants of inhibition of UCP1-mediated respiratory uncoupling
por: Gagelin, Antoine, et al.
Publicado: (2023)

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
por: Wakabayashi, Junko, et al.
Publicado: (2009)

Alterations in c-Myc phenotypes resulting from dynamin-related protein 1 (Drp1)-mediated mitochondrial fission
por: Sarin, M, et al.
Publicado: (2013)

Phosphorylation of Dynamin-Related Protein 1 (DRP1) Regulates Mitochondrial Dynamics and Skeletal Muscle Wasting in Cancer Cachexia
por: Mao, Xiangyu, et al.
Publicado: (2021)

Population Genetic Analysis of the Uncoupling Proteins Supports a Role for UCP3 in Human Cold Resistance
por: Hancock, Angela M., et al.
Publicado: (2011)

Antagonistic effect of TNF-alpha and insulin on uncoupling protein 2 (UCP-2) expression and vascular damage
por: Gómez-Hernández, Almudena, et al.
Publicado: (2014)

Transcriptome Response Signatures Associated with the Overexpression of a Mitochondrial Uncoupling Protein (AtUCP1) in Tobacco
por: Laitz, Alessandra Vasconcellos Nunes, et al.
Publicado: (2015)

Association of Uncoupling Protein 1 (UCP1) gene polymorphism with obesity: a case-control study
por: Chathoth, Shahanas, et al.
Publicado: (2018)

Inhibition of the mitochondrial fission protein dynamin-related protein 1 (Drp1) impairs mitochondrial fission and mitotic catastrophe after x-irradiation
por: Yamamori, Tohru, et al.
Publicado: (2015)

Uncoupling Protein-4 (UCP4) Increases ATP Supply by Interacting with Mitochondrial Complex II in Neuroblastoma Cells
por: Ho, Philip Wing-Lok, et al.
Publicado: (2012)

Mitochondrial Uncoupling Protein-2 (UCP2) Mediates Leptin Protection Against MPP(+) Toxicity in Neuronal Cells
por: Ho, Philip Wing-Lok, et al.
Publicado: (2009)

Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan
por: Fridell, Yih-Woei C., et al.
Publicado: (2009)

Overexpression of mitochondrial uncoupling protein 1 (UCP1) induces a hypoxic response in Nicotiana tabacum leaves
por: Barreto, Pedro, et al.
Publicado: (2016)

UCP-3 uncoupling protein confers hypoxia resistance to renal epithelial cells and is upregulated in renal cell carcinoma
por: Braun, Norbert, et al.
Publicado: (2015)

Role of mitochondrial uncoupling protein-2 (UCP2) in higher brain functions, neuronal plasticity and network oscillation
por: Hermes, Gretchen, et al.
Publicado: (2016)

Uncoupling Protein, UCP-4 May Be Involved in Neuronal Defects During Aging and Resistance to Pathogens in Caenorhabditis elegans
por: Cho, Injeong, et al.
Publicado: (2016)

Uncoupling protein 4 (UCP4) gene variability in neurodegenerative disorders: further evidence of association in Frontotemporal dementia
por: Montesanto, Alberto, et al.
Publicado: (2018)

Mitochondrial Uncoupling Proteins (UCPs) as Key Modulators of ROS Homeostasis: A Crosstalk between Diabesity and Male Infertility?
por: Monteiro, Bruno S., et al.
Publicado: (2021)

Drosophila melanogaster Uncoupling Protein-4A (UCP4A) Catalyzes a Unidirectional Transport of Aspartate
por: Lunetti, Paola, et al.
Publicado: (2022)

Uncoupling Protein-1 (UCP1) in the Adult Horse: Correlations with Body Weight, Rectal Temperature and Lipid Profile
por: Arfuso, Francesca, et al.
Publicado: (2021)

Localization of uncoupling protein 1 (UCP-1) in the sebaceous gland of the dorsal region in the Sunda porcupine (Hystrix javanica)
por: PRAWIRA, Andhika Yudha, et al.
Publicado: (2020)

Human neuronal uncoupling proteins 4 and 5 (UCP4 and UCP5): structural properties, regulation, and physiological role in protection against oxidative stress and mitochondrial dysfunction
por: Ramsden, David B, et al.
Publicado: (2012)

Mitochondrial Uncoupling Proteins (UCP1-UCP3) and Adenine Nucleotide Translocase (ANT1) Enhance the Protonophoric Action of 2,4-Dinitrophenol in Mitochondria and Planar Bilayer Membranes
por: Žuna, Kristina, et al.
Publicado: (2021)

Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy
por: Haileselassie, Bereketeab, et al.
Publicado: (2020)

Correlation Between Pancreatic Islet Uncoupling Protein-2 (UCP2) mRNA Concentration And Insulin Status in Rats
por: Kassis, Nadim, et al.
Publicado: (2000)

The Uncoupling Protein 1 Gene (UCP1) Is Disrupted in the Pig Lineage: A Genetic Explanation for Poor Thermoregulation in Piglets
por: Berg, Frida, et al.
Publicado: (2006)

Analysis of Uncoupling Protein 2-Deficient Mice upon Anaesthesia and Sedation Revealed a Role for UCP2 in Locomotion
por: Alves-Guerra, Marie-Clotilde, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_nhqvvkllanmjink38g8b8h9r8p