Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections

Acute bacterial infections are often treated empirically, with the choice of antibiotic therapy updated during treatment. The effects of such rapid antibiotic switching on the evolution of antibiotic resistance in individual patients are poorly understood. Here we find that low-frequency antibiotic...

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Detalles Bibliográficos
Autores principales: Chung, Hattie, Merakou, Christina, Schaefers, Matthew M., Flett, Kelly B., Martini, Sarah, Lu, Roger, Blumenthal, Jennifer A., Webster, Shanice S., Cross, Ashley R., Al Ahmar, Roy, Halpin, Erin, Anderson, Michelle, Moore, Nicholas S., Snesrud, Eric C., Yu, Hongwei D., Goldberg, Joanna B., O’Toole, George A., McGann, Patrick, Stam, Jason A., Hinkle, Mary, McAdam, Alexander J., Kishony, Roy, Priebe, Gregory P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907320/
https://www.ncbi.nlm.nih.gov/pubmed/35264582
http://dx.doi.org/10.1038/s41467-022-28188-w

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