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Parathyroid Hormone Regulates Circulating Levels of Sclerostin and FGF23 in a Primary Hyperparathyroidism Model

Parathyroid hormone (PTH) increases fibroblast growth factor 23 (FGF23), mediated both by protein kinase A (PKA) and Wnt signaling, and decreases expression of sclerostin, a Wnt antagonist derived from osteocytes. Patients with primary hyperparathyroidism (PHPT) have lower serum sclerostin levels th...

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Detalles Bibliográficos
Autores principales:	Nagata, Yuki, Imanishi, Yasuo, Tateishi, Tomomi, Miyaoka, Daichi, Kurajoh, Masafumi, Arnold, Andrew, Emoto, Masanori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907412/ https://www.ncbi.nlm.nih.gov/pubmed/35284773 http://dx.doi.org/10.1210/jendso/bvac027

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