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Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells

Human natural killer (NK) cells can target tumor cells in an antigen-specific manner by the recognition of cell bound antibodies. This process induces antibody-dependent cell-mediated cytotoxicity (ADCC) and is exclusively mediated by the low affinity IgG Fc receptor CD16A (FcγRIIIA). Exploiting ADC...

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Detalles Bibliográficos
Autores principales: Hullsiek, Robert, Li, Yunfang, Snyder, Kristin M., Wang, Sam, Di, Da, Borgatti, Antonella, Lee, Chae, Moore, Peter F., Zhu, Cong, Fattori, Chiara, Modiano, Jaime F., Wu, Jianming, Walcheck, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907477/
https://www.ncbi.nlm.nih.gov/pubmed/35281028
http://dx.doi.org/10.3389/fimmu.2022.841859