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Activation of LXR Nuclear Receptors Impairs the Anti-Inflammatory Gene and Functional Profile of M-CSF-Dependent Human Monocyte-Derived Macrophages

Liver X Receptors (LXR) control cholesterol metabolism and exert anti-inflammatory actions but their contribution to human macrophage polarization remains unclear. The LXR pathway is enriched in pro-inflammatory macrophages from rheumatoid arthritis as well as in tumors-associated macrophages from h...

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Detalles Bibliográficos
Autores principales:	González de la Aleja, Arturo, Herrero, Cristina, Torres-Torresano, Mónica, de la Rosa, Juan Vladimir, Alonso, Bárbara, Capa-Sardón, Enrique, Muller, Ittai B., Jansen, Gerrit, Puig-Kröger, Amaya, Vega, Miguel A., Castrillo, Antonio, Corbí, Ángel L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907538/ https://www.ncbi.nlm.nih.gov/pubmed/35280993 http://dx.doi.org/10.3389/fimmu.2022.835478

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