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Co-Expression and Combined Prognostic Value of CSPG4 and PDL1 in TP53-Aberrant Triple-Negative Breast Cancer

BACKGROUND: In triple-negative breast cancer (TNBC), PDL1/PD1-directed immunotherapy is effective in less than 20% of patients. In our preliminary study, we have found CSPG4 to be highly expressed together with PDL1 in TNBCs, particularly those harboring TP53 aberrations. However, the clinical impli...

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Detalles Bibliográficos
Autores principales: Hu, Zhe-Yu, Zheng, Chanjuan, Yang, Jianbo, Ding, Siyu, Tian, Can, Xie, Ning, Xue, Lian, Wu, Muyao, Fu, Shujun, Rao, Zhouzhou, Price, Matthew A., McCarthy, James B., Ouyang, Quchang, Lin, Jizhen, Deng, Xiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907582/
https://www.ncbi.nlm.nih.gov/pubmed/35280756
http://dx.doi.org/10.3389/fonc.2022.804466