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Case Report: Pemphigus in Young Patients With Thymic Anomalies

Pemphigus is an autoimmune disease that occurs mainly in elderly individuals. Young patients with pemphigus are rare, and the risk factors are unclear. The thymus is associated with a variety of autoimmune diseases, and there have been reports of pemphigus complicated with thymic diseases. Here, we...

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Autores principales: Lin, Naiyu, Li, Xiaoli, Lang, Yuejiao, Han, Jiande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907624/
https://www.ncbi.nlm.nih.gov/pubmed/35280858
http://dx.doi.org/10.3389/fmed.2022.844223
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author Lin, Naiyu
Li, Xiaoli
Lang, Yuejiao
Han, Jiande
author_facet Lin, Naiyu
Li, Xiaoli
Lang, Yuejiao
Han, Jiande
author_sort Lin, Naiyu
collection PubMed
description Pemphigus is an autoimmune disease that occurs mainly in elderly individuals. Young patients with pemphigus are rare, and the risk factors are unclear. The thymus is associated with a variety of autoimmune diseases, and there have been reports of pemphigus complicated with thymic diseases. Here, we report three cases of young patients with pemphigus that were associated with thymic anomalies. We suggest that thymic anomalies may be a risk factor for the early onset of pemphigus and may be associated with increased severity of the disease. Interventions for thymic diseases have certain benefits for improving the effect of treatments and prognosis of these patients.
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spelling pubmed-89076242022-03-11 Case Report: Pemphigus in Young Patients With Thymic Anomalies Lin, Naiyu Li, Xiaoli Lang, Yuejiao Han, Jiande Front Med (Lausanne) Medicine Pemphigus is an autoimmune disease that occurs mainly in elderly individuals. Young patients with pemphigus are rare, and the risk factors are unclear. The thymus is associated with a variety of autoimmune diseases, and there have been reports of pemphigus complicated with thymic diseases. Here, we report three cases of young patients with pemphigus that were associated with thymic anomalies. We suggest that thymic anomalies may be a risk factor for the early onset of pemphigus and may be associated with increased severity of the disease. Interventions for thymic diseases have certain benefits for improving the effect of treatments and prognosis of these patients. Frontiers Media S.A. 2022-02-24 /pmc/articles/PMC8907624/ /pubmed/35280858 http://dx.doi.org/10.3389/fmed.2022.844223 Text en Copyright © 2022 Lin, Li, Lang and Han. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Lin, Naiyu
Li, Xiaoli
Lang, Yuejiao
Han, Jiande
Case Report: Pemphigus in Young Patients With Thymic Anomalies
title Case Report: Pemphigus in Young Patients With Thymic Anomalies
title_full Case Report: Pemphigus in Young Patients With Thymic Anomalies
title_fullStr Case Report: Pemphigus in Young Patients With Thymic Anomalies
title_full_unstemmed Case Report: Pemphigus in Young Patients With Thymic Anomalies
title_short Case Report: Pemphigus in Young Patients With Thymic Anomalies
title_sort case report: pemphigus in young patients with thymic anomalies
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907624/
https://www.ncbi.nlm.nih.gov/pubmed/35280858
http://dx.doi.org/10.3389/fmed.2022.844223
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