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Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy

STUDY DESIGN: Retrospective case series. OBJECTIVES: To evaluate the variability in opioid prescription following primary single-level lumbar microdiscectomy. METHODS: We retrospectively reviewed consecutive patients who underwent primary single-level lumbar microdiscectomy. Only opioid-naïve patien...

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Autores principales: Le, Hai, Phan, Eileen, Agatstein, Lauren, Barber, Joshua, Klineberg, Eric, Roberto, Rolando, Javidan, Yashar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907642/
https://www.ncbi.nlm.nih.gov/pubmed/32856480
http://dx.doi.org/10.1177/2192568220950678
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author Le, Hai
Phan, Eileen
Agatstein, Lauren
Barber, Joshua
Klineberg, Eric
Roberto, Rolando
Javidan, Yashar
author_facet Le, Hai
Phan, Eileen
Agatstein, Lauren
Barber, Joshua
Klineberg, Eric
Roberto, Rolando
Javidan, Yashar
author_sort Le, Hai
collection PubMed
description STUDY DESIGN: Retrospective case series. OBJECTIVES: To evaluate the variability in opioid prescription following primary single-level lumbar microdiscectomy. METHODS: We retrospectively reviewed consecutive patients who underwent primary single-level lumbar microdiscectomy. Only opioid-naïve patients ≥18 years old were included. Patients who had revision microdiscectomy, multilevel decompression, and/or any complication requiring prolonged hospital stay (>2 days) were excluded. The primary outcomes were the maximum daily dosage of opioids prescribed in morphine milligram equivalents (MME) and the number of pills prescribed (equivalent to 5 mg hydrocodone). RESULTS: Between 2014 and 2019, 169 patients (90 men, 79 women) met inclusion criteria, with a mean age of 46.9 years. Surgery resulted in a statistically significant improvement in VAS (Visual Analogue Scale) score (6.4 to 2.5, P < .01). At discharge, 8 patients (4.7%) did not receive any opioid prescription. Of the remaining 161 patients, 1 patient (0.01%) received hydromorphone, 30 (18.6%) Percocet, 43 (26.7%) oxycodone, and 87 Norco (54.0%). The length of opioid prescription was 6.7 days. The maximum daily dosage of opioids prescribed was 70.4 MME (SD 32.1). The total number of pills prescribed was 89.4 (SD 54.7). Twenty-five patients (15.5%) received a refill prescription. Multivariate analysis demonstrated the operating service, prescriber, and hospital admission were statistically significant predictors of maximum daily MME. The prescriber and hospital admission were statistically significant predictors of total number of pills prescribed. CONCLUSIONS: We found significant variability in opioid prescription following primary single-level lumbar microdiscectomy. For standard spinal procedures like lumbar microdiscectomy, opioid-prescribing guidelines should be established to standardize postoperative pain management.
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spelling pubmed-89076422022-03-11 Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy Le, Hai Phan, Eileen Agatstein, Lauren Barber, Joshua Klineberg, Eric Roberto, Rolando Javidan, Yashar Global Spine J Original Articles STUDY DESIGN: Retrospective case series. OBJECTIVES: To evaluate the variability in opioid prescription following primary single-level lumbar microdiscectomy. METHODS: We retrospectively reviewed consecutive patients who underwent primary single-level lumbar microdiscectomy. Only opioid-naïve patients ≥18 years old were included. Patients who had revision microdiscectomy, multilevel decompression, and/or any complication requiring prolonged hospital stay (>2 days) were excluded. The primary outcomes were the maximum daily dosage of opioids prescribed in morphine milligram equivalents (MME) and the number of pills prescribed (equivalent to 5 mg hydrocodone). RESULTS: Between 2014 and 2019, 169 patients (90 men, 79 women) met inclusion criteria, with a mean age of 46.9 years. Surgery resulted in a statistically significant improvement in VAS (Visual Analogue Scale) score (6.4 to 2.5, P < .01). At discharge, 8 patients (4.7%) did not receive any opioid prescription. Of the remaining 161 patients, 1 patient (0.01%) received hydromorphone, 30 (18.6%) Percocet, 43 (26.7%) oxycodone, and 87 Norco (54.0%). The length of opioid prescription was 6.7 days. The maximum daily dosage of opioids prescribed was 70.4 MME (SD 32.1). The total number of pills prescribed was 89.4 (SD 54.7). Twenty-five patients (15.5%) received a refill prescription. Multivariate analysis demonstrated the operating service, prescriber, and hospital admission were statistically significant predictors of maximum daily MME. The prescriber and hospital admission were statistically significant predictors of total number of pills prescribed. CONCLUSIONS: We found significant variability in opioid prescription following primary single-level lumbar microdiscectomy. For standard spinal procedures like lumbar microdiscectomy, opioid-prescribing guidelines should be established to standardize postoperative pain management. SAGE Publications 2020-08-28 2022-03 /pmc/articles/PMC8907642/ /pubmed/32856480 http://dx.doi.org/10.1177/2192568220950678 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (https://creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Le, Hai
Phan, Eileen
Agatstein, Lauren
Barber, Joshua
Klineberg, Eric
Roberto, Rolando
Javidan, Yashar
Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy
title Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy
title_full Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy
title_fullStr Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy
title_full_unstemmed Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy
title_short Variability in Opioid Prescription Following Primary Single-Level Lumbar Microdiscectomy
title_sort variability in opioid prescription following primary single-level lumbar microdiscectomy
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907642/
https://www.ncbi.nlm.nih.gov/pubmed/32856480
http://dx.doi.org/10.1177/2192568220950678
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