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The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review

Approximately 1.5 million people in the United States currently identify as transgender. The use of gender affirming hormone therapy is integral to routine clinical care of transgender individuals, yet our understanding of the effects of this therapy is limited. There are reasons to believe that gen...

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Autores principales: Chan Swe, Nyein, Ahmed, Samihah, Eid, Marwen, Poretsky, Leonid, Gianos, Eugenia, Cusano, Natalie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907681/
https://www.ncbi.nlm.nih.gov/pubmed/35282421
http://dx.doi.org/10.1016/j.metop.2022.100173
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author Chan Swe, Nyein
Ahmed, Samihah
Eid, Marwen
Poretsky, Leonid
Gianos, Eugenia
Cusano, Natalie E.
author_facet Chan Swe, Nyein
Ahmed, Samihah
Eid, Marwen
Poretsky, Leonid
Gianos, Eugenia
Cusano, Natalie E.
author_sort Chan Swe, Nyein
collection PubMed
description Approximately 1.5 million people in the United States currently identify as transgender. The use of gender affirming hormone therapy is integral to routine clinical care of transgender individuals, yet our understanding of the effects of this therapy is limited. There are reasons to believe that gender affirming hormone therapy may have important effects on cardiovascular risk and bone health in transgender individuals. The purpose of this review article is to summarize the evidence for the cardiovascular effects (including coronary artery disease, hypertension and stroke) as well as the effects on bone metabolism associated with gender affirming hormone therapy in both transgender men and transgender women.
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spelling pubmed-89076812022-03-11 The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review Chan Swe, Nyein Ahmed, Samihah Eid, Marwen Poretsky, Leonid Gianos, Eugenia Cusano, Natalie E. Metabol Open Review Approximately 1.5 million people in the United States currently identify as transgender. The use of gender affirming hormone therapy is integral to routine clinical care of transgender individuals, yet our understanding of the effects of this therapy is limited. There are reasons to believe that gender affirming hormone therapy may have important effects on cardiovascular risk and bone health in transgender individuals. The purpose of this review article is to summarize the evidence for the cardiovascular effects (including coronary artery disease, hypertension and stroke) as well as the effects on bone metabolism associated with gender affirming hormone therapy in both transgender men and transgender women. Elsevier 2022-03-03 /pmc/articles/PMC8907681/ /pubmed/35282421 http://dx.doi.org/10.1016/j.metop.2022.100173 Text en © 2022 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Chan Swe, Nyein
Ahmed, Samihah
Eid, Marwen
Poretsky, Leonid
Gianos, Eugenia
Cusano, Natalie E.
The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review
title The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review
title_full The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review
title_fullStr The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review
title_full_unstemmed The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review
title_short The effects of gender-affirming hormone therapy on cardiovascular and skeletal health: A literature review
title_sort effects of gender-affirming hormone therapy on cardiovascular and skeletal health: a literature review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907681/
https://www.ncbi.nlm.nih.gov/pubmed/35282421
http://dx.doi.org/10.1016/j.metop.2022.100173
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