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Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report
Mucormycosis is a rare and invasive fungal infection with high mortality. Cases of invasive pulmonary mucormycosis that involve allergic reactions such as allergic bronchopulmonary mycosis are rarely reported. Herein, we describe a case of invasive pulmonary mucormycosis overlapping with allergic di...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907707/ https://www.ncbi.nlm.nih.gov/pubmed/35280885 http://dx.doi.org/10.3389/fmed.2022.831213 |
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author | Zhang, Ruhui Jin, Ge Zhan, Yasheng Shen, Lisha Yao, Yake Gao, Qiqi Yang, Qing Zhou, Jianying Zhou, Hua |
author_facet | Zhang, Ruhui Jin, Ge Zhan, Yasheng Shen, Lisha Yao, Yake Gao, Qiqi Yang, Qing Zhou, Jianying Zhou, Hua |
author_sort | Zhang, Ruhui |
collection | PubMed |
description | Mucormycosis is a rare and invasive fungal infection with high mortality. Cases of invasive pulmonary mucormycosis that involve allergic reactions such as allergic bronchopulmonary mycosis are rarely reported. Herein, we describe a case of invasive pulmonary mucormycosis overlapping with allergic diseases in a patient who presented with eosinophilia and high total plasma immunoglobulin E (IgE). The patient was successfully treated with systemic corticosteroids (initial dose of prednisolone approximately 0.5 mg/kg per day, total duration less than 3 months) combined with posaconazole antifungal therapy. The treatment resulted in recovery of peripheral-blood eosinophil count and total plasma IgE, and significant reduction in lung lesions. A subsequent lobectomy was performed. The findings in this case indicate that systemic corticosteroid therapy may contribute to the treatment of pulmonary mucormycosis combined with allergic factors. |
format | Online Article Text |
id | pubmed-8907707 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89077072022-03-11 Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report Zhang, Ruhui Jin, Ge Zhan, Yasheng Shen, Lisha Yao, Yake Gao, Qiqi Yang, Qing Zhou, Jianying Zhou, Hua Front Med (Lausanne) Medicine Mucormycosis is a rare and invasive fungal infection with high mortality. Cases of invasive pulmonary mucormycosis that involve allergic reactions such as allergic bronchopulmonary mycosis are rarely reported. Herein, we describe a case of invasive pulmonary mucormycosis overlapping with allergic diseases in a patient who presented with eosinophilia and high total plasma immunoglobulin E (IgE). The patient was successfully treated with systemic corticosteroids (initial dose of prednisolone approximately 0.5 mg/kg per day, total duration less than 3 months) combined with posaconazole antifungal therapy. The treatment resulted in recovery of peripheral-blood eosinophil count and total plasma IgE, and significant reduction in lung lesions. A subsequent lobectomy was performed. The findings in this case indicate that systemic corticosteroid therapy may contribute to the treatment of pulmonary mucormycosis combined with allergic factors. Frontiers Media S.A. 2022-02-24 /pmc/articles/PMC8907707/ /pubmed/35280885 http://dx.doi.org/10.3389/fmed.2022.831213 Text en Copyright © 2022 Zhang, Jin, Zhan, Shen, Yao, Gao, Yang, Zhou and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Zhang, Ruhui Jin, Ge Zhan, Yasheng Shen, Lisha Yao, Yake Gao, Qiqi Yang, Qing Zhou, Jianying Zhou, Hua Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report |
title | Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report |
title_full | Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report |
title_fullStr | Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report |
title_full_unstemmed | Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report |
title_short | Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive Pulmonary Mucormycosis: A Case Report |
title_sort | allergic bronchopulmonary mycosis caused by mucor overlapping with invasive pulmonary mucormycosis: a case report |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907707/ https://www.ncbi.nlm.nih.gov/pubmed/35280885 http://dx.doi.org/10.3389/fmed.2022.831213 |
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