MPO-ANCA-positive Microscopic Polyangiitis Following COVID-19 Infection

Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic disease that causes vasculitis in various organs. Although the cause of the onset is unknown, infection has been reported to be a causative factor. The subsequent cytokine storm triggered by the immune response against SAR...

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Detalles Bibliográficos
Autores principales: Kawashima, Soko, Kishimoto, Mitsumasa, Hibino, Tomoya, Lee, Hearyoung, Sato, Yuriko, Komagata, Yoshinori, Kaname, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907777/
https://www.ncbi.nlm.nih.gov/pubmed/34840232
http://dx.doi.org/10.2169/internalmedicine.8615-21
Descripción
Sumario:Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic disease that causes vasculitis in various organs. Although the cause of the onset is unknown, infection has been reported to be a causative factor. The subsequent cytokine storm triggered by the immune response against SARS-CoV-2 infection has been reported to lead to symptoms being more severe. We herein report our experience with the onset of AAV following COVID-19 infection. We also report the course of anti-SARS-CoV-2 serum antibody titers following induction therapy, which suggests that vaccination and education concerning standard precautions are necessary in patients who require immunosuppressive therapy, even after COVID-19 infection.

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