An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome

A 68-year-old woman developed systemic blisters while receiving treatment for nephrotic syndrome. As she also developed marked liver dysfunction and disseminated intravascular coagulation, she was admitted to our hospital. She was diagnosed with varicella zoster virus (VZV) infection. Treatment was...

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Autores principales: Kuwano, Katsuhisa, Ota, Yuki, Tsuji, Kiyokazu, Torigoe, Kenta, Yamashita, Ayuko, Muta, Kumiko, Kitamura, Mineaki, Yamashita, Hiroshi, Uramatsu, Tadashi, Tashiro, Masato, Hayashi, Hiroko, Izumikawa, Koichi, Mukae, Hiroshi, Nishino, Tomoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907779/
https://www.ncbi.nlm.nih.gov/pubmed/34393162
http://dx.doi.org/10.2169/internalmedicine.7332-21
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author Kuwano, Katsuhisa
Ota, Yuki
Tsuji, Kiyokazu
Torigoe, Kenta
Yamashita, Ayuko
Muta, Kumiko
Kitamura, Mineaki
Yamashita, Hiroshi
Uramatsu, Tadashi
Tashiro, Masato
Hayashi, Hiroko
Izumikawa, Koichi
Mukae, Hiroshi
Nishino, Tomoya
author_facet Kuwano, Katsuhisa
Ota, Yuki
Tsuji, Kiyokazu
Torigoe, Kenta
Yamashita, Ayuko
Muta, Kumiko
Kitamura, Mineaki
Yamashita, Hiroshi
Uramatsu, Tadashi
Tashiro, Masato
Hayashi, Hiroko
Izumikawa, Koichi
Mukae, Hiroshi
Nishino, Tomoya
author_sort Kuwano, Katsuhisa
collection PubMed
description A 68-year-old woman developed systemic blisters while receiving treatment for nephrotic syndrome. As she also developed marked liver dysfunction and disseminated intravascular coagulation, she was admitted to our hospital. She was diagnosed with varicella zoster virus (VZV) infection. Treatment was administered in the intensive-care unit, but the patient died on day 24 post-admission after severe VZV infection. A post-mortem examination showed micro-abscesses and necrosis caused by varicella zoster infection in multiple organs, including the liver, kidneys, and gastrointestinal tract. Because VZV infection can become severe in immunocompromised patients, careful consideration is needed for the prevention and treatment of the viral infection.
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spelling pubmed-89077792022-03-25 An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome Kuwano, Katsuhisa Ota, Yuki Tsuji, Kiyokazu Torigoe, Kenta Yamashita, Ayuko Muta, Kumiko Kitamura, Mineaki Yamashita, Hiroshi Uramatsu, Tadashi Tashiro, Masato Hayashi, Hiroko Izumikawa, Koichi Mukae, Hiroshi Nishino, Tomoya Intern Med Case Report A 68-year-old woman developed systemic blisters while receiving treatment for nephrotic syndrome. As she also developed marked liver dysfunction and disseminated intravascular coagulation, she was admitted to our hospital. She was diagnosed with varicella zoster virus (VZV) infection. Treatment was administered in the intensive-care unit, but the patient died on day 24 post-admission after severe VZV infection. A post-mortem examination showed micro-abscesses and necrosis caused by varicella zoster infection in multiple organs, including the liver, kidneys, and gastrointestinal tract. Because VZV infection can become severe in immunocompromised patients, careful consideration is needed for the prevention and treatment of the viral infection. The Japanese Society of Internal Medicine 2021-08-13 2022-02-15 /pmc/articles/PMC8907779/ /pubmed/34393162 http://dx.doi.org/10.2169/internalmedicine.7332-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kuwano, Katsuhisa
Ota, Yuki
Tsuji, Kiyokazu
Torigoe, Kenta
Yamashita, Ayuko
Muta, Kumiko
Kitamura, Mineaki
Yamashita, Hiroshi
Uramatsu, Tadashi
Tashiro, Masato
Hayashi, Hiroko
Izumikawa, Koichi
Mukae, Hiroshi
Nishino, Tomoya
An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome
title An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome
title_full An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome
title_fullStr An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome
title_full_unstemmed An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome
title_short An Autopsy Case of Disseminated Varicella Zoster Virus Infection during the Treatment of Nephrotic Syndrome
title_sort autopsy case of disseminated varicella zoster virus infection during the treatment of nephrotic syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907779/
https://www.ncbi.nlm.nih.gov/pubmed/34393162
http://dx.doi.org/10.2169/internalmedicine.7332-21
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