Understanding the Unique Microenvironment in the Aging Liver

In the past decades, many studies have focused on aging because of our pursuit of longevity. With lifespans extended, the regenerative capacity of the liver gradually declines due to the existence of aging. This is partially due to the unique microenvironment in the aged liver, which affects a serie...

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Detalles Bibliográficos
Autores principales: Zhao, Yalei, Yang, Ya, Li, Qian, Li, Jianzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907916/
https://www.ncbi.nlm.nih.gov/pubmed/35280864
http://dx.doi.org/10.3389/fmed.2022.842024
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author Zhao, Yalei
Yang, Ya
Li, Qian
Li, Jianzhou
author_facet Zhao, Yalei
Yang, Ya
Li, Qian
Li, Jianzhou
author_sort Zhao, Yalei
collection PubMed
description In the past decades, many studies have focused on aging because of our pursuit of longevity. With lifespans extended, the regenerative capacity of the liver gradually declines due to the existence of aging. This is partially due to the unique microenvironment in the aged liver, which affects a series of physiological processes. In this review, we summarize the related researches in the last decade and try to highlight the aging-related alterations in the aged liver.
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spelling pubmed-89079162022-03-11 Understanding the Unique Microenvironment in the Aging Liver Zhao, Yalei Yang, Ya Li, Qian Li, Jianzhou Front Med (Lausanne) Medicine In the past decades, many studies have focused on aging because of our pursuit of longevity. With lifespans extended, the regenerative capacity of the liver gradually declines due to the existence of aging. This is partially due to the unique microenvironment in the aged liver, which affects a series of physiological processes. In this review, we summarize the related researches in the last decade and try to highlight the aging-related alterations in the aged liver. Frontiers Media S.A. 2022-02-24 /pmc/articles/PMC8907916/ /pubmed/35280864 http://dx.doi.org/10.3389/fmed.2022.842024 Text en Copyright © 2022 Zhao, Yang, Li and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Zhao, Yalei
Yang, Ya
Li, Qian
Li, Jianzhou
Understanding the Unique Microenvironment in the Aging Liver
title Understanding the Unique Microenvironment in the Aging Liver
title_full Understanding the Unique Microenvironment in the Aging Liver
title_fullStr Understanding the Unique Microenvironment in the Aging Liver
title_full_unstemmed Understanding the Unique Microenvironment in the Aging Liver
title_short Understanding the Unique Microenvironment in the Aging Liver
title_sort understanding the unique microenvironment in the aging liver
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907916/
https://www.ncbi.nlm.nih.gov/pubmed/35280864
http://dx.doi.org/10.3389/fmed.2022.842024
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