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Chlorovirus ATCV-1 Accelerates Motor Deterioration in SOD1-G93A Transgenic Mice and Its SOD1 Augments Induction of Inflammatory Factors From Murine Macrophages

BACKGROUND: Genetically polymorphic Superoxide Dismutase 1 G93A (SOD1-G93A) underlies one form of familial Amyotrophic Lateral Sclerosis (ALS). Exposures from viruses may also contribute to ALS, possibly by stimulating immune factors, such as IL-6, Interferon Stimulated Genes, and Nitric Oxide. Rece...

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Detalles Bibliográficos
Autores principales:	Petro, Thomas M., Agarkova, Irina V., Esmael, Ahmed, Dunigan, David D., Van Etten, James L., Pattee, Gary L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908019/ https://www.ncbi.nlm.nih.gov/pubmed/35280283 http://dx.doi.org/10.3389/fneur.2022.821166

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