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Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension

INTRODUCTION: Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition associated with high morbidity and mortality. However, advances in medical, surgical and interventional treatment have markedly improved the outcome of patients with CTEPH. Additional fact...

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Autores principales: Lepsy, Nicole, Dering, Madelaine-Rachel, Fuge, Jan, Meltendorf, Tanja, Hoeper, Marius M., Heitland, Ivo, Kamp, Jan C., Park, Da-Hee, Richter, Manuel J., Gall, Henning, Ghofrani, Hossein A., Ellermeier, Dietmar, Kulla, Hans-Dieter, Olsson, Karen M., Kahl, Kai G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908105/
https://www.ncbi.nlm.nih.gov/pubmed/35280158
http://dx.doi.org/10.3389/fpsyt.2022.821468
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author Lepsy, Nicole
Dering, Madelaine-Rachel
Fuge, Jan
Meltendorf, Tanja
Hoeper, Marius M.
Heitland, Ivo
Kamp, Jan C.
Park, Da-Hee
Richter, Manuel J.
Gall, Henning
Ghofrani, Hossein A.
Ellermeier, Dietmar
Kulla, Hans-Dieter
Olsson, Karen M.
Kahl, Kai G.
author_facet Lepsy, Nicole
Dering, Madelaine-Rachel
Fuge, Jan
Meltendorf, Tanja
Hoeper, Marius M.
Heitland, Ivo
Kamp, Jan C.
Park, Da-Hee
Richter, Manuel J.
Gall, Henning
Ghofrani, Hossein A.
Ellermeier, Dietmar
Kulla, Hans-Dieter
Olsson, Karen M.
Kahl, Kai G.
author_sort Lepsy, Nicole
collection PubMed
description INTRODUCTION: Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition associated with high morbidity and mortality. However, advances in medical, surgical and interventional treatment have markedly improved the outcome of patients with CTEPH. Additional factors potentially influencing quality of life (QoL) and outcome in CTEPH are yet to be defined. Child maltreatment is a major risk factor for unfavorable behavioral, mental as well as physical health outcomes and has been associated with decreased QoL. To date, no study assessed the impact of childhood trauma in patients with CTEPH. METHODS: Patients with CTEPH were invited to complete the Childhood Trauma Questionnaire (CTQ). Data were compared to prevalence data from the German population. Mental well-being was assessed using the Hospital Anxiety and Depression Scale (HADS) and quality of life was measured using the WHO Quality of Life Questionnaire (WHOQOL). Furthermore, lifestyle factors and physical health parameters were studied. Logistic regression analysis was used to investigate a possible impact of child maltreatment on markers of disease severity. RESULTS: One-hundred and seven patients with CTEPH completed the CTQ. These patients reported higher rates of emotional abuse and physical abuse and emotional neglect compared to the German population while rates of physical neglect and sexual abuse did not differ between patients and German population with prevalence of 20.6% for emotional abuse, 20% for physical abuse, 22% for emotional neglect, 46% for physical neglect, and 6% for sexual abuse in patients with CTEPH. Higher CTQ scores were associated with anxiety symptoms as well as negatively associated with QoL. No direct impact of childhood trauma on CTEPH severity was found. CONCLUSION: We found a higher rate of child maltreatment in patients with CTEPH in comparison to the German population. Correlations suggest moderate associations between CTQ scores and mental health and QoL. Child maltreatment had no significant impact on disease severity. Further investigation on proper interventions to support affected patients is needed.
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spelling pubmed-89081052022-03-11 Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension Lepsy, Nicole Dering, Madelaine-Rachel Fuge, Jan Meltendorf, Tanja Hoeper, Marius M. Heitland, Ivo Kamp, Jan C. Park, Da-Hee Richter, Manuel J. Gall, Henning Ghofrani, Hossein A. Ellermeier, Dietmar Kulla, Hans-Dieter Olsson, Karen M. Kahl, Kai G. Front Psychiatry Psychiatry INTRODUCTION: Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially life-threatening condition associated with high morbidity and mortality. However, advances in medical, surgical and interventional treatment have markedly improved the outcome of patients with CTEPH. Additional factors potentially influencing quality of life (QoL) and outcome in CTEPH are yet to be defined. Child maltreatment is a major risk factor for unfavorable behavioral, mental as well as physical health outcomes and has been associated with decreased QoL. To date, no study assessed the impact of childhood trauma in patients with CTEPH. METHODS: Patients with CTEPH were invited to complete the Childhood Trauma Questionnaire (CTQ). Data were compared to prevalence data from the German population. Mental well-being was assessed using the Hospital Anxiety and Depression Scale (HADS) and quality of life was measured using the WHO Quality of Life Questionnaire (WHOQOL). Furthermore, lifestyle factors and physical health parameters were studied. Logistic regression analysis was used to investigate a possible impact of child maltreatment on markers of disease severity. RESULTS: One-hundred and seven patients with CTEPH completed the CTQ. These patients reported higher rates of emotional abuse and physical abuse and emotional neglect compared to the German population while rates of physical neglect and sexual abuse did not differ between patients and German population with prevalence of 20.6% for emotional abuse, 20% for physical abuse, 22% for emotional neglect, 46% for physical neglect, and 6% for sexual abuse in patients with CTEPH. Higher CTQ scores were associated with anxiety symptoms as well as negatively associated with QoL. No direct impact of childhood trauma on CTEPH severity was found. CONCLUSION: We found a higher rate of child maltreatment in patients with CTEPH in comparison to the German population. Correlations suggest moderate associations between CTQ scores and mental health and QoL. Child maltreatment had no significant impact on disease severity. Further investigation on proper interventions to support affected patients is needed. Frontiers Media S.A. 2022-02-24 /pmc/articles/PMC8908105/ /pubmed/35280158 http://dx.doi.org/10.3389/fpsyt.2022.821468 Text en Copyright © 2022 Lepsy, Dering, Fuge, Meltendorf, Hoeper, Heitland, Kamp, Park, Richter, Gall, Ghofrani, Ellermeier, Kulla, Olsson and Kahl. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Lepsy, Nicole
Dering, Madelaine-Rachel
Fuge, Jan
Meltendorf, Tanja
Hoeper, Marius M.
Heitland, Ivo
Kamp, Jan C.
Park, Da-Hee
Richter, Manuel J.
Gall, Henning
Ghofrani, Hossein A.
Ellermeier, Dietmar
Kulla, Hans-Dieter
Olsson, Karen M.
Kahl, Kai G.
Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
title Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
title_full Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
title_fullStr Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
title_full_unstemmed Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
title_short Childhood Maltreatment, Mental Well-Being, and Healthy Lifestyle in Patients With Chronic Thromboembolic Pulmonary Hypertension
title_sort childhood maltreatment, mental well-being, and healthy lifestyle in patients with chronic thromboembolic pulmonary hypertension
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908105/
https://www.ncbi.nlm.nih.gov/pubmed/35280158
http://dx.doi.org/10.3389/fpsyt.2022.821468
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