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Novel germline mutation in lung cancer pedigrees establishes BCAR1 as a human cancer susceptibility gene: a case report

BACKGROUND: Lung cancer is the most prevalent malignancy worldwide. Most cases are sporadic and carry somatic mutations in hotspot genes. However, accumulating studies have identified several germline mutations that predispose patients to lung cancer at present. CASE DESCRIPTION: In this report, 2 s...

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Detalles Bibliográficos
Autores principales: Zhu, Kuikui, Zhao, Yingchao, Zhang, Sijia, Wu, Lu, Zong, Yan, Li, Zhenyu, Li, Qianwen, Cheng, Fang, Meng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908131/
https://www.ncbi.nlm.nih.gov/pubmed/35280415
http://dx.doi.org/10.21037/atm-21-7017