Levosimendan protects from sepsis-inducing cardiac dysfunction by suppressing inflammation, oxidative stress and regulating cardiac mitophagy via the PINK-1-Parkin pathway in mice

BACKGROUND: Sepsis is a leading cause of death in China, the mortality rate of which is elevated when cardiac dysfunction is induced. Levosimendan is used for the treatment of decompensated cardiac failure. In this study, we sought to investigate the role of levosimendan in the inflammation, oxidati...

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Detalles Bibliográficos
Autores principales: Shi, Jian, Chen, Yuhong, Zhi, Haijun, An, Hui, Hu, Zhenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908175/
https://www.ncbi.nlm.nih.gov/pubmed/35280364
http://dx.doi.org/10.21037/atm-22-483

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