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IKKα contributes to ischemia-induced autophagy after acute cerebral ischemic injury

BACKGROUND: The function of IκB kinase α (IKKα) in the brain is largely unknown. This study examined the effects of IKKα on autophagy after cerebral ischemia. METHODS: Permanent distal middle cerebral artery occlusion (dMCAO) was conducted in C57/BL6 mice. Oxygen-glucose deprivation/reperfusion (OGD...

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Detalles Bibliográficos
Autores principales: Dong, Wen, Chen, Qingfang, Zhao, Shunying, Wen, Shaohong, Chen, Wentao, Ye, Weizhen, Gong, Ting, Jiang, Mingyu, Liu, Xiangrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908181/
https://www.ncbi.nlm.nih.gov/pubmed/35280366
http://dx.doi.org/10.21037/atm-22-517