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Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure

Heart failure (HF) is one of the main public health problems at present. Although some breakthroughs have been made in the treatment of HF, the mortality rate remains very high. However, we should also pay attention to improving the quality of life of patients with HF. Traditional Chinese medicine (...

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Autores principales: Wang, Anzhu, Zhao, Wei, Yan, Kaituo, Huang, Pingping, Zhang, Hongwei, Zhang, Zhibo, Zhang, Dawu, Ma, Xiaochang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908244/
https://www.ncbi.nlm.nih.gov/pubmed/35281941
http://dx.doi.org/10.3389/fphar.2022.810587
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author Wang, Anzhu
Zhao, Wei
Yan, Kaituo
Huang, Pingping
Zhang, Hongwei
Zhang, Zhibo
Zhang, Dawu
Ma, Xiaochang
author_facet Wang, Anzhu
Zhao, Wei
Yan, Kaituo
Huang, Pingping
Zhang, Hongwei
Zhang, Zhibo
Zhang, Dawu
Ma, Xiaochang
author_sort Wang, Anzhu
collection PubMed
description Heart failure (HF) is one of the main public health problems at present. Although some breakthroughs have been made in the treatment of HF, the mortality rate remains very high. However, we should also pay attention to improving the quality of life of patients with HF. Traditional Chinese medicine (TCM) has a long history of being used to treat HF. To demonstrate the clinical effects and mechanisms of TCM, we searched published clinical trial studies and basic studies. The search results showed that adjuvant therapy with TCM might benefit patients with HF, and its mechanism may be related to microvascular circulation, myocardial energy metabolism, oxidative stress, and inflammation.
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spelling pubmed-89082442022-03-11 Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure Wang, Anzhu Zhao, Wei Yan, Kaituo Huang, Pingping Zhang, Hongwei Zhang, Zhibo Zhang, Dawu Ma, Xiaochang Front Pharmacol Pharmacology Heart failure (HF) is one of the main public health problems at present. Although some breakthroughs have been made in the treatment of HF, the mortality rate remains very high. However, we should also pay attention to improving the quality of life of patients with HF. Traditional Chinese medicine (TCM) has a long history of being used to treat HF. To demonstrate the clinical effects and mechanisms of TCM, we searched published clinical trial studies and basic studies. The search results showed that adjuvant therapy with TCM might benefit patients with HF, and its mechanism may be related to microvascular circulation, myocardial energy metabolism, oxidative stress, and inflammation. Frontiers Media S.A. 2022-02-24 /pmc/articles/PMC8908244/ /pubmed/35281941 http://dx.doi.org/10.3389/fphar.2022.810587 Text en Copyright © 2022 Wang, Zhao, Yan, Huang, Zhang, Zhang, Zhang and Ma. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Wang, Anzhu
Zhao, Wei
Yan, Kaituo
Huang, Pingping
Zhang, Hongwei
Zhang, Zhibo
Zhang, Dawu
Ma, Xiaochang
Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
title Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
title_full Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
title_fullStr Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
title_full_unstemmed Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
title_short Mechanisms and Efficacy of Traditional Chinese Medicine in Heart Failure
title_sort mechanisms and efficacy of traditional chinese medicine in heart failure
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908244/
https://www.ncbi.nlm.nih.gov/pubmed/35281941
http://dx.doi.org/10.3389/fphar.2022.810587
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