Exosomal miR-673-5p from fibroblasts promotes Schwann cell-mediated peripheral neuron myelination by targeting the TSC2/mTORC1/SREBP2 axis

Peripheral myelination is a complicated process, wherein Schwann cells (SCs) promote the formation of the myelin sheath around the axons of peripheral neurons. Fibroblasts are the second resident cells in the peripheral nerves; however, the precise function of fibroblasts in SC-mediated myelination...

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Detalles Bibliográficos
Autores principales: Zhao, Yahong, Liang, Yunyun, Xu, Zhixin, Liu, Jina, Liu, Xiaoyu, Ma, Jinyu, Sun, Cheng, Yang, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908274/
https://www.ncbi.nlm.nih.gov/pubmed/35151688
http://dx.doi.org/10.1016/j.jbc.2022.101718

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