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Enhanced Top-Down Protein Characterization with Electron Capture Dissociation and Cyclic Ion Mobility Spectrometry

[Image: see text] Tandem mass spectrometry of denatured, multiply charged high mass protein precursor ions yield extremely dense spectra with hundreds of broad and overlapping product ion isotopic distributions of differing charge states that yield an elevated baseline of unresolved “noise” centered...

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Detalles Bibliográficos
Autores principales:	Shaw, Jared B., Cooper-Shepherd, Dale A., Hewitt, Darren, Wildgoose, Jason L., Beckman, Joseph S., Langridge, James I., Voinov, Valery G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908312/ https://www.ncbi.nlm.nih.gov/pubmed/35188751 http://dx.doi.org/10.1021/acs.analchem.1c04870

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