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Efficacy and safety of biologic agents for the treatment of osteoarthritis: a meta-analysis of randomized placebo-controlled trials

BACKGROUND: We aimed to evaluate the efficacy and safety of biologic agents targeting three main cytokines, that is, nerve growth factor (NGF), interleukin-1 (IL-1), and tumor necrosis factor-α (TNF-α), for osteoarthritis (OA) treatment. METHODS: Databases (PubMed, Embase, and Cochrane Library) and...

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Detalles Bibliográficos
Autores principales:	Meng, Fanqiang, Li, Hui, Feng, Haoran, Long, Huizhong, Yang, Zidan, Li, Jiatian, Wang, Yuqing, Xie, Dongxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Addressing the Challenges Associated with the Development, Testing and Approval of Novel Therapeutics for Osteoarthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908403/ https://www.ncbi.nlm.nih.gov/pubmed/35282570 http://dx.doi.org/10.1177/1759720X221080377

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