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Facile Multicomponent Synthesis, Computational, and Docking Studies of Spiroindoloquinazoline Compounds

[Image: see text] Synthesis of spiroindoloquinazolines via one-pot three-component condensation reactions of tryptanthrin, malononitrile or ethylcyanoacetate, and nucleophiles was carried out in MeOH using triethylamine as the base catalyst under reflux conditions. This method has the advantages of...

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Detalles Bibliográficos
Autores principales: Palapetta, Surya Cholayil, Gurusamy, Harichandran, Krishnan, Sarojinidevi, Ponnusamy, Shanmugam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908518/
https://www.ncbi.nlm.nih.gov/pubmed/35284703
http://dx.doi.org/10.1021/acsomega.1c06781