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Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia

BACKGROUND: Acute respiratory tract infection (ARI) is one of the leading causes of illness and mortality in children under the age of five worldwide. Pneumonia, which is caused by a respiratory tract infection, kills about 1.9 million children under the age of 5 years around the world. The majority...

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Autores principales: Merera, Amanuel, Asena, Tilahun, Senbeta, Mebratu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908561/
https://www.ncbi.nlm.nih.gov/pubmed/35272658
http://dx.doi.org/10.1186/s12887-022-03187-4
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author Merera, Amanuel
Asena, Tilahun
Senbeta, Mebratu
author_facet Merera, Amanuel
Asena, Tilahun
Senbeta, Mebratu
author_sort Merera, Amanuel
collection PubMed
description BACKGROUND: Acute respiratory tract infection (ARI) is one of the leading causes of illness and mortality in children under the age of five worldwide. Pneumonia, which is caused by a respiratory tract infection, kills about 1.9 million children under the age of 5 years around the world. The majority of these deaths occur in underdeveloped countries. According to the 2016 Ethiopia Demographic and Health Survey (EDHS), the prevalence rate of ARI in Ethiopia was 7%. Prevalence is defined as the number of infectious diseases present at a given period in relation to the total number of children under the age of five who have been exposed to ARI. The goal of this study was to determine the risk factors for acute respiratory infection among children under the age of five in Ethiopia. METHODS: To provide representative samples of the population, a community-based cross-sectional sampling scheme was designed. Bayesian multilevel approach was employed to assess factors associated with the prevalence of ARI among children under age five in Ethiopia. The data was collected from 10,641 children under the age of 5 years out of which 9918 children were considered in this study. RESULTS: The ARI prevalence rate in children under the age of 5 years was assessed to be 8.4%, somewhat higher than the country’s anticipated prevalence rate. Children whose mothers did not have a high level of education had the highest prevalence of ARI. The key health, environmental, and nutritional factors influencing the proportion of children with ARI differed by area. Tigray (15.3%) and Oromia (14.4%) had the highest prevalence of ARI, while Benishangul Gumuz had the lowest prevalence (2.6%). The use of vitamin A was investigated, and the results revealed that roughly 43.1% of those who received vitamin A had the lowest prevalence of ARI (7.7%) as compared to those who did not receive vitamin A. Diarrhea affected 11.1% of children under the age of five, with the highest frequency of ARI (24.6%) and the highest prevalence of ARI reported in children whose drinking water source was unprotected/unimproved (9.4%). CONCLUSIONS: The prevalence of ARI among children under the age of 5 years was found to be strongly affected by the child’s age, household wealth index, mother’s educational level, vitamin A supplement, history of diarrhea, maternal work, stunting, and drinking water source. The study also found that the incidence of ARI varies significantly between and within Ethiopian areas. When intending to improve the health status of Ethiopian children, those predictive variables should be taken into consideration. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-022-03187-4.
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spelling pubmed-89085612022-03-18 Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia Merera, Amanuel Asena, Tilahun Senbeta, Mebratu BMC Pediatr Research BACKGROUND: Acute respiratory tract infection (ARI) is one of the leading causes of illness and mortality in children under the age of five worldwide. Pneumonia, which is caused by a respiratory tract infection, kills about 1.9 million children under the age of 5 years around the world. The majority of these deaths occur in underdeveloped countries. According to the 2016 Ethiopia Demographic and Health Survey (EDHS), the prevalence rate of ARI in Ethiopia was 7%. Prevalence is defined as the number of infectious diseases present at a given period in relation to the total number of children under the age of five who have been exposed to ARI. The goal of this study was to determine the risk factors for acute respiratory infection among children under the age of five in Ethiopia. METHODS: To provide representative samples of the population, a community-based cross-sectional sampling scheme was designed. Bayesian multilevel approach was employed to assess factors associated with the prevalence of ARI among children under age five in Ethiopia. The data was collected from 10,641 children under the age of 5 years out of which 9918 children were considered in this study. RESULTS: The ARI prevalence rate in children under the age of 5 years was assessed to be 8.4%, somewhat higher than the country’s anticipated prevalence rate. Children whose mothers did not have a high level of education had the highest prevalence of ARI. The key health, environmental, and nutritional factors influencing the proportion of children with ARI differed by area. Tigray (15.3%) and Oromia (14.4%) had the highest prevalence of ARI, while Benishangul Gumuz had the lowest prevalence (2.6%). The use of vitamin A was investigated, and the results revealed that roughly 43.1% of those who received vitamin A had the lowest prevalence of ARI (7.7%) as compared to those who did not receive vitamin A. Diarrhea affected 11.1% of children under the age of five, with the highest frequency of ARI (24.6%) and the highest prevalence of ARI reported in children whose drinking water source was unprotected/unimproved (9.4%). CONCLUSIONS: The prevalence of ARI among children under the age of 5 years was found to be strongly affected by the child’s age, household wealth index, mother’s educational level, vitamin A supplement, history of diarrhea, maternal work, stunting, and drinking water source. The study also found that the incidence of ARI varies significantly between and within Ethiopian areas. When intending to improve the health status of Ethiopian children, those predictive variables should be taken into consideration. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12887-022-03187-4. BioMed Central 2022-03-10 /pmc/articles/PMC8908561/ /pubmed/35272658 http://dx.doi.org/10.1186/s12887-022-03187-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Merera, Amanuel
Asena, Tilahun
Senbeta, Mebratu
Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
title Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
title_full Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
title_fullStr Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
title_full_unstemmed Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
title_short Bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in Ethiopia
title_sort bayesian multilevel analysis of determinants of acute respiratory infection in children under the age of five years in ethiopia
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908561/
https://www.ncbi.nlm.nih.gov/pubmed/35272658
http://dx.doi.org/10.1186/s12887-022-03187-4
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