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Aloe vera and Streptozotocin-Induced Diabetes Mellitus
Diabetes mellitus is defined as prolonged hyperglycemia, which can harm the eyes, kidneys, and cardiovascular and neurological systems. Herbal agents and their derived supplements have been used for treatment of diabetes mellitus as a part of integrated complementary medicine for centuries. Numerous...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908758/ https://www.ncbi.nlm.nih.gov/pubmed/35287334 http://dx.doi.org/10.1007/s43450-022-00231-3 |
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author | Haghani, Fatemeh Arabnezhad, Mohammad-Reza Mohammadi, Salman Ghaffarian-Bahraman, Ali |
author_facet | Haghani, Fatemeh Arabnezhad, Mohammad-Reza Mohammadi, Salman Ghaffarian-Bahraman, Ali |
author_sort | Haghani, Fatemeh |
collection | PubMed |
description | Diabetes mellitus is defined as prolonged hyperglycemia, which can harm the eyes, kidneys, and cardiovascular and neurological systems. Herbal agents and their derived supplements have been used for treatment of diabetes mellitus as a part of integrated complementary medicine for centuries. Numerous studies have considered Aloe vera (L.) Burm.f, Xanthorrhoeaceae, as an alternative medicine due to its abundant bioactive chemicals, such as alkaloids, anthraquinones, and enthrones, with therapeutical properties including antioxidant, anti-inflammatory, neuro-protective, and anti-diabetic effects. Aloe vera has received considerable attention in traditional medicine for the treatment of several diseases including diabetes mellitus. Numerous studies have investigated the effects of herbal agents on diabetes mellitus using a streptozotocin-induced diabetic model. Thereby, this article reviews the effects of Aloe vera prescription on streptozotocin-induced diabetes mellitus to provide a clear insight into the role of this medicinal plant in several biological functions, such as antioxidant, wound healing, anti-inflammatory, anti-hyperglycemic, and anti-hyperlipidemic in diabetic models. [Figure: see text] |
format | Online Article Text |
id | pubmed-8908758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-89087582022-03-10 Aloe vera and Streptozotocin-Induced Diabetes Mellitus Haghani, Fatemeh Arabnezhad, Mohammad-Reza Mohammadi, Salman Ghaffarian-Bahraman, Ali Rev Bras Farmacogn Review Diabetes mellitus is defined as prolonged hyperglycemia, which can harm the eyes, kidneys, and cardiovascular and neurological systems. Herbal agents and their derived supplements have been used for treatment of diabetes mellitus as a part of integrated complementary medicine for centuries. Numerous studies have considered Aloe vera (L.) Burm.f, Xanthorrhoeaceae, as an alternative medicine due to its abundant bioactive chemicals, such as alkaloids, anthraquinones, and enthrones, with therapeutical properties including antioxidant, anti-inflammatory, neuro-protective, and anti-diabetic effects. Aloe vera has received considerable attention in traditional medicine for the treatment of several diseases including diabetes mellitus. Numerous studies have investigated the effects of herbal agents on diabetes mellitus using a streptozotocin-induced diabetic model. Thereby, this article reviews the effects of Aloe vera prescription on streptozotocin-induced diabetes mellitus to provide a clear insight into the role of this medicinal plant in several biological functions, such as antioxidant, wound healing, anti-inflammatory, anti-hyperglycemic, and anti-hyperlipidemic in diabetic models. [Figure: see text] Springer International Publishing 2022-03-10 2022 /pmc/articles/PMC8908758/ /pubmed/35287334 http://dx.doi.org/10.1007/s43450-022-00231-3 Text en © The Author(s) under exclusive licence to Sociedade Brasileira de Farmacognosia 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Review Haghani, Fatemeh Arabnezhad, Mohammad-Reza Mohammadi, Salman Ghaffarian-Bahraman, Ali Aloe vera and Streptozotocin-Induced Diabetes Mellitus |
title | Aloe vera and Streptozotocin-Induced Diabetes Mellitus |
title_full | Aloe vera and Streptozotocin-Induced Diabetes Mellitus |
title_fullStr | Aloe vera and Streptozotocin-Induced Diabetes Mellitus |
title_full_unstemmed | Aloe vera and Streptozotocin-Induced Diabetes Mellitus |
title_short | Aloe vera and Streptozotocin-Induced Diabetes Mellitus |
title_sort | aloe vera and streptozotocin-induced diabetes mellitus |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908758/ https://www.ncbi.nlm.nih.gov/pubmed/35287334 http://dx.doi.org/10.1007/s43450-022-00231-3 |
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