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Japanese Encephalitis Virus Persistence in Porcine Tonsils Is Associated With a Weak Induction of the Innate Immune Response, an Absence of IFNγ mRNA Expression, and a Decreased Frequency of CD4(+)CD8(+) Double-Positive T Cells
In humans, Japanese encephalitis virus (JEV) causes a devastating neurotropic disease with high mortality, whereas in pigs, the virus only causes mild symptoms. Besides tropism to the central nervous system, JEV seems to harbor a particular tropism for the tonsils in pigs. This secondary lymphoid or...
Autores principales: | Redant, Valerie, Favoreel, Herman W., Dallmeier, Kai, Van Campe, Willem, De Regge, Nick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908958/ https://www.ncbi.nlm.nih.gov/pubmed/35281443 http://dx.doi.org/10.3389/fcimb.2022.834888 |
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