Cargando…
Noncoding RNAs in Cardiac Hypertrophy and Heart Failure
Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in physiological processes and in the pathogenesis of various diseases, including heart failure. ncRNAs have emerged as critical components of transcriptional regulatory pathways that govern cardiac development, str...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908994/ https://www.ncbi.nlm.nih.gov/pubmed/35269399 http://dx.doi.org/10.3390/cells11050777 |
_version_ | 1784666001022910464 |
---|---|
author | Lu, Peilei Ding, Fan Xiang, Yang Kevin Hao, Liying Zhao, Meimi |
author_facet | Lu, Peilei Ding, Fan Xiang, Yang Kevin Hao, Liying Zhao, Meimi |
author_sort | Lu, Peilei |
collection | PubMed |
description | Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in physiological processes and in the pathogenesis of various diseases, including heart failure. ncRNAs have emerged as critical components of transcriptional regulatory pathways that govern cardiac development, stress response, signaling, and remodeling in cardiac pathology. Recently, studies of ncRNAs in cardiovascular disease have achieved significant development. Here, we discuss the roles of ncRNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs) that modulate the cardiac hypertrophy and heart failure. |
format | Online Article Text |
id | pubmed-8908994 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89089942022-03-11 Noncoding RNAs in Cardiac Hypertrophy and Heart Failure Lu, Peilei Ding, Fan Xiang, Yang Kevin Hao, Liying Zhao, Meimi Cells Review Heart failure is a major global health concern. Noncoding RNAs (ncRNAs) are involved in physiological processes and in the pathogenesis of various diseases, including heart failure. ncRNAs have emerged as critical components of transcriptional regulatory pathways that govern cardiac development, stress response, signaling, and remodeling in cardiac pathology. Recently, studies of ncRNAs in cardiovascular disease have achieved significant development. Here, we discuss the roles of ncRNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs) that modulate the cardiac hypertrophy and heart failure. MDPI 2022-02-23 /pmc/articles/PMC8908994/ /pubmed/35269399 http://dx.doi.org/10.3390/cells11050777 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lu, Peilei Ding, Fan Xiang, Yang Kevin Hao, Liying Zhao, Meimi Noncoding RNAs in Cardiac Hypertrophy and Heart Failure |
title | Noncoding RNAs in Cardiac Hypertrophy and Heart Failure |
title_full | Noncoding RNAs in Cardiac Hypertrophy and Heart Failure |
title_fullStr | Noncoding RNAs in Cardiac Hypertrophy and Heart Failure |
title_full_unstemmed | Noncoding RNAs in Cardiac Hypertrophy and Heart Failure |
title_short | Noncoding RNAs in Cardiac Hypertrophy and Heart Failure |
title_sort | noncoding rnas in cardiac hypertrophy and heart failure |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8908994/ https://www.ncbi.nlm.nih.gov/pubmed/35269399 http://dx.doi.org/10.3390/cells11050777 |
work_keys_str_mv | AT lupeilei noncodingrnasincardiachypertrophyandheartfailure AT dingfan noncodingrnasincardiachypertrophyandheartfailure AT xiangyangkevin noncodingrnasincardiachypertrophyandheartfailure AT haoliying noncodingrnasincardiachypertrophyandheartfailure AT zhaomeimi noncodingrnasincardiachypertrophyandheartfailure |