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Pathological Relevance of Post-Translationally Modified Alpha-Synuclein (pSer87, pSer129, nTyr39) in Idiopathic Parkinson’s Disease and Multiple System Atrophy

Aggregated alpha-synuclein (α-synuclein) is the main component of Lewy bodies (LBs), Lewy neurites (LNs), and glial cytoplasmic inclusions (GCIs), which are pathological hallmarks of idiopathic Parkinson’s disease (IPD) and multiple system atrophy (MSA). Initiating factors that culminate in forming...

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Detalles Bibliográficos
Autores principales: Sonustun, Berkiye, Altay, Melek Firat, Strand, Catherine, Ebanks, Kirsten, Hondhamuni, Geshanthi, Warner, Thomas T., Lashuel, Hilal A., Bandopadhyay, Rina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909017/
https://www.ncbi.nlm.nih.gov/pubmed/35269528
http://dx.doi.org/10.3390/cells11050906