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Impact of UGT1A1 Polymorphisms on Febrile Neutropenia in Pancreatic Cancer Patients Receiving FOLFIRINOX: A Single-Center Cohort Study

SIMPLE SUMMARY: FOLFIRINOX, which is a first-line chemotherapy for metastatic pancreatic cancer, has become one of the high-risk regimens related to developing febrile neutropenia (FN). Although UGT1A1 polymorphisms are associated with the metabolism of irinotecan, their role as surrogate markers fo...

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Detalles Bibliográficos
Autores principales:	Keum, Jiyoung, Lee, Hee Seung, Jo, Jung Hyun, Chung, Moon Jae, Park, Jeong Youp, Park, Seung Woo, Song, Si Young, Bang, Seungmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909027/ https://www.ncbi.nlm.nih.gov/pubmed/35267552 http://dx.doi.org/10.3390/cancers14051244

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