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Role of Furin in Colon Cancer Stem Cells Malignant Phenotype and Expression of LGR5 and NANOG in KRAS and BRAF-Mutated Colon Tumors

SIMPLE SUMMARY: Colorectal cancer (CRC) is one of the most common malignancies in the digestive system. We have previously shown that the proprotein convertase Furin is involved in calcium regulation in cancer cells. In this study, we revealed that the malignant phenotype of colon cancer stem cells...

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Detalles Bibliográficos
Autores principales:	Descarpentrie, Jean, Araúzo-Bravo, Marcos J., He, Zongsheng, François, Alexia, González, Álvaro, Garcia-Gallastegi, Patricia, Badiola, Iker, Evrard, Serge, Pernot, Simon, Creemers, John W. M., Khatib, Abdel-Majid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909039/ https://www.ncbi.nlm.nih.gov/pubmed/35267511 http://dx.doi.org/10.3390/cancers14051195

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