Border Line Definition Using Hyperspectral Imaging in Colorectal Resections

SIMPLE SUMMARY: Good oxygenation of both bowel ends is an important prerequisite to promote anastomotic healing after colorectal resections. Bowel oxygenation is usually assessed clinically. Hyperspectral imaging is a contactless and contrast-free tool that allows quantifying tissue oxygen intraoper...

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Autores principales: Jansen-Winkeln, Boris, Dvorak, Michelle, Köhler, Hannes, Maktabi, Marianne, Mehdorn, Matthias, Chalopin, Claire, Diana, Michele, Gockel, Ines, Barberio, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909141/
https://www.ncbi.nlm.nih.gov/pubmed/35267496
http://dx.doi.org/10.3390/cancers14051188
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author Jansen-Winkeln, Boris
Dvorak, Michelle
Köhler, Hannes
Maktabi, Marianne
Mehdorn, Matthias
Chalopin, Claire
Diana, Michele
Gockel, Ines
Barberio, Manuel
author_facet Jansen-Winkeln, Boris
Dvorak, Michelle
Köhler, Hannes
Maktabi, Marianne
Mehdorn, Matthias
Chalopin, Claire
Diana, Michele
Gockel, Ines
Barberio, Manuel
author_sort Jansen-Winkeln, Boris
collection PubMed
description SIMPLE SUMMARY: Good oxygenation of both bowel ends is an important prerequisite to promote anastomotic healing after colorectal resections. Bowel oxygenation is usually assessed clinically. Hyperspectral imaging is a contactless and contrast-free tool that allows quantifying tissue oxygen intraoperatively. In this study, the results of 105 colorectal resections with hyperspectral imaging are reported. ABSTRACT: Background: A perfusion deficit is a well-defined and intraoperatively influenceable cause of anastomotic leak (AL). Current intraoperative perfusion assessment methods do not provide objective and quantitative results. In this study, the ability of hyperspectral imaging (HSI) to quantify tissue oxygenation intraoperatively was assessed. Methods: 115 patients undergoing colorectal resections were included in the final analysis. Before anastomotic formation, the bowel was extracted and the resection line was outlined and imaged using a compact HSI camera, in order to provide instantaneously quantitative perfusion assessment. Results: In 105 patients, a clear demarcation line was visible with HSI one minute after marginal artery transection, reaching a plateau after 3 min. In 58 (55.2%) patients, the clinically determined transection line matched with HSI. In 23 (21.9%) patients, the clinically established resection margin was entirely within the less perfused area. In 24 patients (22.8%), the HSI transection line had an irregular course and crossed the clinically established resection line. In four cases, HSI disclosed a clinically undetected lesion of the marginal artery. Conclusions: Intraoperative HSI is safe, well reproducible, and does not disrupt the surgical workflow. It also quantifies bowel surface perfusion. HSI might become an intraoperative guidance tool, potentially preventing postoperative complications.
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spelling pubmed-89091412022-03-11 Border Line Definition Using Hyperspectral Imaging in Colorectal Resections Jansen-Winkeln, Boris Dvorak, Michelle Köhler, Hannes Maktabi, Marianne Mehdorn, Matthias Chalopin, Claire Diana, Michele Gockel, Ines Barberio, Manuel Cancers (Basel) Article SIMPLE SUMMARY: Good oxygenation of both bowel ends is an important prerequisite to promote anastomotic healing after colorectal resections. Bowel oxygenation is usually assessed clinically. Hyperspectral imaging is a contactless and contrast-free tool that allows quantifying tissue oxygen intraoperatively. In this study, the results of 105 colorectal resections with hyperspectral imaging are reported. ABSTRACT: Background: A perfusion deficit is a well-defined and intraoperatively influenceable cause of anastomotic leak (AL). Current intraoperative perfusion assessment methods do not provide objective and quantitative results. In this study, the ability of hyperspectral imaging (HSI) to quantify tissue oxygenation intraoperatively was assessed. Methods: 115 patients undergoing colorectal resections were included in the final analysis. Before anastomotic formation, the bowel was extracted and the resection line was outlined and imaged using a compact HSI camera, in order to provide instantaneously quantitative perfusion assessment. Results: In 105 patients, a clear demarcation line was visible with HSI one minute after marginal artery transection, reaching a plateau after 3 min. In 58 (55.2%) patients, the clinically determined transection line matched with HSI. In 23 (21.9%) patients, the clinically established resection margin was entirely within the less perfused area. In 24 patients (22.8%), the HSI transection line had an irregular course and crossed the clinically established resection line. In four cases, HSI disclosed a clinically undetected lesion of the marginal artery. Conclusions: Intraoperative HSI is safe, well reproducible, and does not disrupt the surgical workflow. It also quantifies bowel surface perfusion. HSI might become an intraoperative guidance tool, potentially preventing postoperative complications. MDPI 2022-02-25 /pmc/articles/PMC8909141/ /pubmed/35267496 http://dx.doi.org/10.3390/cancers14051188 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jansen-Winkeln, Boris
Dvorak, Michelle
Köhler, Hannes
Maktabi, Marianne
Mehdorn, Matthias
Chalopin, Claire
Diana, Michele
Gockel, Ines
Barberio, Manuel
Border Line Definition Using Hyperspectral Imaging in Colorectal Resections
title Border Line Definition Using Hyperspectral Imaging in Colorectal Resections
title_full Border Line Definition Using Hyperspectral Imaging in Colorectal Resections
title_fullStr Border Line Definition Using Hyperspectral Imaging in Colorectal Resections
title_full_unstemmed Border Line Definition Using Hyperspectral Imaging in Colorectal Resections
title_short Border Line Definition Using Hyperspectral Imaging in Colorectal Resections
title_sort border line definition using hyperspectral imaging in colorectal resections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909141/
https://www.ncbi.nlm.nih.gov/pubmed/35267496
http://dx.doi.org/10.3390/cancers14051188
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