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DNA Repair Enzyme Poly(ADP-Ribose) Polymerase 1/2 (PARP1/2)-Targeted Nuclear Imaging and Radiotherapy

SIMPLE SUMMARY: In parallel to the successful clinical implementation of PARP1/2 inhibitors as anti-cancer drugs, which interfere with the DNA repair machinery, these small molecule agents have also gained attention as vehicles for molecular imaging and radiotherapy. In this review article, we summa...

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Detalles Bibliográficos
Autores principales: Nguyen, Nghia T., Pacelli, Anna, Nader, Michael, Kossatz, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909184/
https://www.ncbi.nlm.nih.gov/pubmed/35267438
http://dx.doi.org/10.3390/cancers14051129