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Targeting Ribosome Biogenesis to Combat Tamoxifen Resistance in ER+ve Breast Cancer
SIMPLE SUMMARY: Resistance to tamoxifen treatment is an obstacle for ER+ve breast cancer therapy. The overexpression of c-MYC is a known driver of cancer progression and is associated with tamoxifen resistance. Through mediating the up-regulation of ribosome biogenesis and alteration of the transcri...
Autores principales: | Tsoi, Ho, You, Chan-Ping, Leung, Man-Hong, Man, Ellen P. S., Khoo, Ui-Soon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909264/ https://www.ncbi.nlm.nih.gov/pubmed/35267559 http://dx.doi.org/10.3390/cancers14051251 |
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