Role of the Skin Microenvironment in Melanomagenesis: Epidermal Keratinocytes and Dermal Fibroblasts Promote BRAF Oncogene-Induced Senescence Escape in Melanocytes

SIMPLE SUMMARY: Melanoma is a deadly skin cancer caused by the uncontrolled proliferation of melanocytes, a population of specialized cells that produce the skin pigment melanin. An aberrant proliferation of melanocytes is common, manifesting as new moles, and these lesions often remain benign. Only...

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Detalles Bibliográficos
Autores principales: Sadangi, Shreyans, Milosavljevic, Katarina, Castro-Perez, Edgardo, Lares, Marcos, Singh, Mithalesh, Altameemi, Sarah, Beebe, David J., Ayuso, Jose M., Setaluri, Vijayasaradhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909265/
https://www.ncbi.nlm.nih.gov/pubmed/35267541
http://dx.doi.org/10.3390/cancers14051233

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