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Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway

SIMPLE SUMMARY: Advanced renal cell carcinoma (RCC) remains an incurable disease, despite the establishment of new therapeutic options during the last decades. Unfortunately, drug resistance inevitably evolves, making better treatment strategies essential. Shikonin (SHI) from traditional Chinese med...

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Detalles Bibliográficos
Autores principales:	Markowitsch, Sascha D., Vakhrusheva, Olesya, Schupp, Patricia, Akele, Yasminn, Kitanovic, Jovana, Slade, Kimberly S., Efferth, Thomas, Thomas, Anita, Tsaur, Igor, Mager, René, Haferkamp, Axel, Juengel, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909272/ https://www.ncbi.nlm.nih.gov/pubmed/35267423 http://dx.doi.org/10.3390/cancers14051114

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