Whole and Purified Aqueous Extracts of Nigella sativa L. Seeds Attenuate Apoptosis and the Overproduction of Reactive Oxygen Species Triggered by p53 Over-Expression in the Yeast Saccharomyces cerevisiae

Plants are an important source of pharmacologically active compounds. In the present work, we characterize the impact of black cumin (Nigella sativa L.) aqueous extracts on a yeast model of p53-dependent apoptosis. To this end, the Saccharomyces cerevisiae recombinant strain over-expressing p53 was...

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Detalles Bibliográficos
Autores principales: Mihoubi, Wafa, Sahli, Emna, Rezgui, Fatma, Dabebi, Najeh, Sayehi, Rabiaa, Hassairi, Hajer, Masmoudi-Fourati, Najla, Walha, Kamel, ben Khadhra, Khalifa, Baklouti, Mohamed, Ghzaiel, Imen, Fattouch, Sami, Menif, Hela, Mokdad-Gargouri, Raja, Lizard, Gérard, Gargouri, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909299/
https://www.ncbi.nlm.nih.gov/pubmed/35269491
http://dx.doi.org/10.3390/cells11050869

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