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Biglycan Interacts with Type I Insulin-like Receptor (IGF-IR) Signaling Pathway to Regulate Osteosarcoma Cell Growth and Response to Chemotherapy

SIMPLE SUMMARY: Osteosarcoma (OS) is an aggressive, primary bone cancer. OS cells produce altered osteoid whose components participate in signaling correlated to the development of this cancer. Biglycan (BGN), a proteoglycan, is correlated to aggressive OS type and resistance to chemotherapy. A cons...

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Detalles Bibliográficos
Autores principales:	Giatagana, Eirini-Maria, Berdiaki, Aikaterini, Gaardløs, Margrethe, Samsonov, Sergey A., Tzanakakis, George N., Nikitovic, Dragana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909324/ https://www.ncbi.nlm.nih.gov/pubmed/35267503 http://dx.doi.org/10.3390/cancers14051196

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