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Role of the Circadian Clock “Death-Loop” in the DNA Damage Response Underpinning Cancer Treatment Resistance

Here, we review the role of the circadian clock (CC) in the resistance of cancer cells to genotoxic treatments in relation to whole-genome duplication (WGD) and telomere-length regulation. The CC drives the normal cell cycle, tissue differentiation, and reciprocally regulates telomere elongation. Ho...

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Detalles Bibliográficos
Autores principales:	Vainshelbaum, Ninel Miriam, Salmina, Kristine, Gerashchenko, Bogdan I., Lazovska, Marija, Zayakin, Pawel, Cragg, Mark Steven, Pjanova, Dace, Erenpreisa, Jekaterina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909334/ https://www.ncbi.nlm.nih.gov/pubmed/35269502 http://dx.doi.org/10.3390/cells11050880

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