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Evaluation of Neurofilament Light Chain as a Biomarker of Neurodegeneration in X-Linked Childhood Cerebral Adrenoleukodystrophy
Cerebral adrenoleukodystrophy (CALD) is a devastating, demyelinating neuroinflammatory manifestation found in up to 40% of young males with an inherited mutation in ABCD1, the causative gene in adrenoleukodystrophy. The search for biomarkers which correlate to CALD disease burden and respond to inte...
Autores principales: | Wang, Hongge, Davison, Matthew D., Kramer, Martin L., Qiu, Weiliang, Gladysheva, Tatiana, Chiang, Ruby M. S., Kayatekin, Can, Nascene, David R., Taghizadeh, Leyla A., King, Carina J., Nolan, Erin E., Gupta, Ashish O., Orchard, Paul J., Lund, Troy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909395/ https://www.ncbi.nlm.nih.gov/pubmed/35269535 http://dx.doi.org/10.3390/cells11050913 |
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