Cargando…

The Osteocyte Stimulated by Wnt Agonist SKL2001 Is a Safe Osteogenic Niche Improving Bioactivities in a Polycaprolactone and Cell Integrated 3D Module

Finding and constructing an osteogenic microenvironment similar to natural bone tissue has always been a frontier topic in orthopedics. We found that osteocytes are targeting cells controlling bone anabolism produced by PTH (JBMR 2017, PMID: 27704638), and osteocytes with activated Wnt signaling orc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yangxi, Ruan, Xiaojie, Li, Jun, Wang, Bo, Chen, Jie, Wang, Xiaofang, Wang, Pengtao, Tu, Xiaolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909416/ https://www.ncbi.nlm.nih.gov/pubmed/35269452 http://dx.doi.org/10.3390/cells11050831

Ejemplares similares

CHIR99021-Treated Osteocytes with Wnt Activation in 3D-Printed Module Form an Osteogenic Microenvironment for Enhanced Osteogenesis and Vasculogenesis
por: Luo, Yisheng, et al.
Publicado: (2023)

SKL1 Is Essential for Chloroplast Development in Arabidopsis
por: Xu, Huimin, et al.
Publicado: (2018)

Activating Wnt/β-Catenin Signaling in Osteocytes Promotes Osteogenic Differentiation of BMSCs through BMP-7
por: Zhang, Yining, et al.
Publicado: (2022)

A Highly Selective GSK-3β Inhibitor CHIR99021 Promotes Osteogenesis by Activating Canonical and Autophagy-Mediated Wnt Signaling
por: Wang, Bo, et al.
Publicado: (2022)

A novel decellularized matrix of Wnt signaling-activated osteocytes accelerates the repair of critical-sized parietal bone defects with osteoclastogenesis, angiogenesis, and neurogenesis
por: Wang, Xiaofang, et al.
Publicado: (2022)

Sustained release of a highly specific GSK3β inhibitor SB216763 in the PCL scaffold creates an osteogenic niche for osteogenesis, anti-adipogenesis, and potential angiogenesis
por: Gong, Weimin, et al.
Publicado: (2023)

Physicochemical Niche Conditions and Mechanosensing by Osteocytes and Myocytes
por: Jin, Jianfeng, et al.
Publicado: (2019)

Stat3 in osteocytes mediates osteogenic response to loading
por: Corry, Kylie A., et al.
Publicado: (2019)

Regulation of Drought and Salt Tolerance by OsSKL2 and OsASR1 in Rice
por: Jiang, Yingli, et al.
Publicado: (2022)

Polydatin Incorporated in Polycaprolactone Nanofibers Improves Osteogenic Differentiation
por: Lama, Stefania, et al.
Publicado: (2022)

Osteocytes Specific GSK3 Inhibition Affects In Vitro Osteogenic Differentiation
por: Bertacchini, Jessika, et al.
Publicado: (2018)

Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
por: Zhang, Bin, et al.
Publicado: (2023)

Sclerostin, Osteocytes, and Wnt Signaling in Pediatric Renal Osteodystrophy
por: Laster, Marciana, et al.
Publicado: (2023)

Functionalization of Electrospun Polycaprolactone Scaffolds with Matrix-Binding Osteocyte-Derived Extracellular Vesicles Promotes Osteoblastic Differentiation and Mineralization
por: Nieuwoudt, Mechiel, et al.
Publicado: (2021)

Failure Analysis of Tension Clamps (SKL15) Used in Serviced Urban Railway Tracks: Numerical Analyses and Experiments
por: Choi, Jung-Youl, et al.
Publicado: (2022)

Gastric inhibitory polypeptide receptor antagonist, SKL‐14959, suppressed body weight gain on diet‐induced obesity mice
por: Nakamura, T., et al.
Publicado: (2018)

Osteogenic Potential of Pre-Osteoblastic Cells on a Chitosan-graft-Polycaprolactone Copolymer
por: Georgopoulou, Anthie, et al.
Publicado: (2018)

IL‐17 alters the mesenchymal stem cell niche towards osteogenesis in cooperation with osteocytes
por: Liao, Chongshan, et al.
Publicado: (2019)

Antimicrobial and Pro-Osteogenic Coaxially Electrospun Magnesium Oxide Nanoparticles-Polycaprolactone /Parathyroid Hormone-Polycaprolactone Composite Barrier Membrane for Guided Bone Regeneration
por: Dong, Yiwen, et al.
Publicado: (2023)

Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes
por: Kratochvilova, Adela, et al.
Publicado: (2021)

Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis
por: Le, Phuong M., et al.
Publicado: (2018)

Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity
por: Gallego-Páramo, Cristina, et al.
Publicado: (2021)

Utilizing Osteocyte Derived Factors to Enhance Cell Viability and Osteogenic Matrix Deposition within IPN Hydrogels
por: Parmentier, Laurens, et al.
Publicado: (2020)

Breast Cancer Cells Metastasize to the Tissue-Engineered Premetastatic Niche by Using an Osteoid-Formed Polycaprolactone/Nanohydroxyapatite Scaffold
por: Xiong, Qisheng, et al.
Publicado: (2021)

Enhanced biocompatibility and osteogenic potential of mesoporous magnesium silicate/polycaprolactone/wheat protein composite scaffolds
por: Kang, Yun Gyeong, et al.
Publicado: (2018)

Comparison between hydroxyapatite and polycaprolactone in inducing osteogenic differentiation and augmenting maxillary bone regeneration in rats
por: Luchman, Nur Atmaliya, et al.
Publicado: (2022)

Effects of E’Jiao on Skeletal Mineralisation, Osteocyte and WNT Signalling Inhibitors in Ovariectomised Rats
por: Chin, Kok-Yong, et al.
Publicado: (2023)

Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation
por: Prideaux, Matthew, et al.
Publicado: (2021)

The Amazing Osteocyte
por: Bonewald, Lynda F
Publicado: (2011)

Osteocytes and Weightlessness
por: Iandolo, Donata, et al.
Publicado: (2021)

Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis
por: Tian, Xiao-Jun, et al.
Publicado: (2020)

Osteocyte Shape and Mechanical Loading
por: van Oers, René F. M., et al.
Publicado: (2015)

Boosting the Osteogenic and Angiogenic Performance of Multiscale Porous Polycaprolactone Scaffolds by In Vitro Generated Extracellular Matrix Decoration
por: Aldemir Dikici, Betül, et al.
Publicado: (2020)

Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
por: Jackson, Erica, et al.
Publicado: (2021)

Notch3 signaling between myeloma cells and osteocytes in the tumor niche promotes tumor growth and bone destruction
por: Sabol, Hayley M., et al.
Publicado: (2022)

NPNT promotes early-stage bone metastases in breast cancer by regulation of the osteogenic niche
por: Wang, Dongsheng, et al.
Publicado: (2018)

Mineralization Content Alters Osteogenic Responses of Bone Marrow Stromal Cells on Hydroxyapatite/Polycaprolactone Composite Nanofiber Scaffolds
por: Ruckh, Timothy T., et al.
Publicado: (2012)

Polycaprolactone nanofiber scaffold enhances the osteogenic differentiation potency of various human tissue-derived mesenchymal stem cells
por: Xue, Ruyue, et al.
Publicado: (2017)

Composite Hydrogel of Methacrylated Hyaluronic Acid and Fragmented Polycaprolactone Nanofiber for Osteogenic Differentiation of Adipose-Derived Stem Cells
por: Patel, Madhumita, et al.
Publicado: (2020)

Amine Plasma-Polymerization of 3D Polycaprolactone/β-Tricalcium Phosphate Scaffold to Improving Osteogenic Differentiation In Vitro
por: Kim, Hee-Yeon, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_k0uju9nelj83q1dbgg22apj3ma