High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand

SIMPLE SUMMARY: Monoclonal antibodies are increasingly used for a broad range of diseases. Rising demand must face with time time-consuming and laborious processes to isolate novel monoclonal antibodies. Next-generation sequencing coupled to phage display provides timely and sustainable high through...

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Detalles Bibliográficos
Autores principales: Zambrano, Nicola, Froechlich, Guendalina, Lazarevic, Dejan, Passariello, Margherita, Nicosia, Alfredo, De Lorenzo, Claudia, Morelli, Marco J., Sasso, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909429/
https://www.ncbi.nlm.nih.gov/pubmed/35267633
http://dx.doi.org/10.3390/cancers14051325

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