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Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center
SIMPLE SUMMARY: BBI608 is an investigational reactive oxygen species generator that affects several molecular and oncogenic pathways, including the STAT3 pathway, and may overcome resistance to immune checkpoint inhibitors. We investigated BBI608 combined with immunotherapy (ipilimumab, pembrolizuma...
Autores principales: | Vo, Henry Hiep, Cartwright, Carrie, Song, I-Wen, Karp, Daniel D., Nogueras Gonzalez, Graciela M., Xie, Yuran, Karol, Michael, Hitron, Matthew, Vining, David, Tsimberidou, Apostolia-Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909492/ https://www.ncbi.nlm.nih.gov/pubmed/35267638 http://dx.doi.org/10.3390/cancers14051330 |
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