Estrogen Receptor-Beta2 (ERβ2)–Mutant p53–FOXM1 Axis: A Novel Driver of Proliferation, Chemoresistance, and Disease Progression in High Grade Serous Ovarian Cancer (HGSOC)

SIMPLE SUMMARY: High grade serous ovarian cancer (HGSOC) is the most common and lethal subtype of ovarian cancer without effective therapeutic options. The high prevalence of mutations (~96%) in tumor suppressor p53 is a hallmark of HGSOC. Estrogen receptor-beta (ERβ) has been reported to be another...

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Detalles Bibliográficos
Autores principales: Oturkar, Chetan C., Gandhi, Nishant, Rao, Pramod, Eng, Kevin H., Miller, Austin, Singh, Prashant K., Zsiros, Emese, Odunsi, Kunle O., Das, Gokul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909529/
https://www.ncbi.nlm.nih.gov/pubmed/35267428
http://dx.doi.org/10.3390/cancers14051120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909529/
https://www.ncbi.nlm.nih.gov/pubmed/35267428
http://dx.doi.org/10.3390/cancers14051120

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