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The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol

This article describes the Salvador Primary Care Longitudinal Study of Child Development (CohortDICa). The exposed group was defined by confirmation of Congenital Zika Syndrome (CZS) diagnosed through computed tomography, magnetic resonance or transfontanellar ultrasound. A random selection of the 1...

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Autores principales: Santos, Darci Neves, de Araújo, Tânia Maria, dos Santos, Leticia Marques, Kuper, Hannah, Aquino, Rosana, Da Silveira, Ismael Henrique, Miranda, Samilly Silva, Pereira, Marcos, Werneck, Guilherme Loureiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909628/
https://www.ncbi.nlm.nih.gov/pubmed/35270212
http://dx.doi.org/10.3390/ijerph19052514
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author Santos, Darci Neves
de Araújo, Tânia Maria
dos Santos, Leticia Marques
Kuper, Hannah
Aquino, Rosana
Da Silveira, Ismael Henrique
Miranda, Samilly Silva
Pereira, Marcos
Werneck, Guilherme Loureiro
author_facet Santos, Darci Neves
de Araújo, Tânia Maria
dos Santos, Leticia Marques
Kuper, Hannah
Aquino, Rosana
Da Silveira, Ismael Henrique
Miranda, Samilly Silva
Pereira, Marcos
Werneck, Guilherme Loureiro
author_sort Santos, Darci Neves
collection PubMed
description This article describes the Salvador Primary Care Longitudinal Study of Child Development (CohortDICa). The exposed group was defined by confirmation of Congenital Zika Syndrome (CZS) diagnosed through computed tomography, magnetic resonance or transfontanellar ultrasound. A random selection of the 169 exposed children led to a subgroup of 120 children who were paired with children from the Live Birth Information System, according to birthdate, residence in the same street or neighborhood, and gestational age, resulting in 115 subjects in the non-exposed group. Following recruitment and before the participants completed 42 months, three measures were applied to assess cognitive, motor, and language performance, corresponding to three home visits. Social characteristics of the families and children, and the neurocognitive development of the children will be compared across the CZS exposed group (n = 147), the typical children with no exposure to CZS (n = 115) and the STORCH exposed group (Syphilis, Toxoplasma gondii, Rubella, Cytomegalovirus, and Herpes simplex) (n = 20). Primary Health Care (PHC) should include long-term care strategies for the care of children and family members, and might benefit from the research, teaching, and extension activities provided in this study. In the face of the consequences of the Zika virus epidemic, an opportunity arose to intervene in the integrated care of child development within PHC, including, on an equal basis, typical children and those with delays or disabilities in the first six years of life.
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spelling pubmed-89096282022-03-11 The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol Santos, Darci Neves de Araújo, Tânia Maria dos Santos, Leticia Marques Kuper, Hannah Aquino, Rosana Da Silveira, Ismael Henrique Miranda, Samilly Silva Pereira, Marcos Werneck, Guilherme Loureiro Int J Environ Res Public Health Study Protocol This article describes the Salvador Primary Care Longitudinal Study of Child Development (CohortDICa). The exposed group was defined by confirmation of Congenital Zika Syndrome (CZS) diagnosed through computed tomography, magnetic resonance or transfontanellar ultrasound. A random selection of the 169 exposed children led to a subgroup of 120 children who were paired with children from the Live Birth Information System, according to birthdate, residence in the same street or neighborhood, and gestational age, resulting in 115 subjects in the non-exposed group. Following recruitment and before the participants completed 42 months, three measures were applied to assess cognitive, motor, and language performance, corresponding to three home visits. Social characteristics of the families and children, and the neurocognitive development of the children will be compared across the CZS exposed group (n = 147), the typical children with no exposure to CZS (n = 115) and the STORCH exposed group (Syphilis, Toxoplasma gondii, Rubella, Cytomegalovirus, and Herpes simplex) (n = 20). Primary Health Care (PHC) should include long-term care strategies for the care of children and family members, and might benefit from the research, teaching, and extension activities provided in this study. In the face of the consequences of the Zika virus epidemic, an opportunity arose to intervene in the integrated care of child development within PHC, including, on an equal basis, typical children and those with delays or disabilities in the first six years of life. MDPI 2022-02-22 /pmc/articles/PMC8909628/ /pubmed/35270212 http://dx.doi.org/10.3390/ijerph19052514 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Study Protocol
Santos, Darci Neves
de Araújo, Tânia Maria
dos Santos, Leticia Marques
Kuper, Hannah
Aquino, Rosana
Da Silveira, Ismael Henrique
Miranda, Samilly Silva
Pereira, Marcos
Werneck, Guilherme Loureiro
The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol
title The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol
title_full The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol
title_fullStr The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol
title_full_unstemmed The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol
title_short The Salvador Primary Care Longitudinal Study of Child Development (CohortDICa) Following the Zika Epidemic: Study Protocol
title_sort salvador primary care longitudinal study of child development (cohortdica) following the zika epidemic: study protocol
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909628/
https://www.ncbi.nlm.nih.gov/pubmed/35270212
http://dx.doi.org/10.3390/ijerph19052514
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