Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms

(1) Background. The endocannabinoid (eCB) system, which regulates physiological and cognitive processes, presents a promising therapeutic target for treating HIV-associated neurocognitive disorders (HAND). Here we examine whether upregulating eCB tone has potential protective effects against HIV-1 T...

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Detalles Bibliográficos
Autores principales: Xu, Changqing, Yadav-Samudrala, Barkha J., Xu, Callie, Nath, Bhupendra, Mistry, Twisha, Jiang, Wei, Niphakis, Micah J., Cravatt, Benjamin F., Mukhopadhyay, Somnath, Lichtman, Aron H., Ignatowska-Jankowska, Bogna M., Fitting, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909692/
https://www.ncbi.nlm.nih.gov/pubmed/35269478
http://dx.doi.org/10.3390/cells11050857

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