Cargando…

DNA Methyltransferase 3b in Myeloid Cells Does Not Affect the Acute Immune Response in the Airways during Pseudomonas Pneumonia

DNA methyltransferase 3b (Dnmt3b) has been suggested to play a role in the host immune response during bacterial infection. Neutrophils and other myeloid cells are crucial for lung defense against Pseudomonas (P.) aeruginosa infection. This study aimed to investigate the role of Dnmt3b in neutrophil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Wanhai, Brands, Xanthe, van’t Veer, Cornelis, de Vos, Alex F., Scicluna, Brendon P., van der Poll, Tom
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909799/ https://www.ncbi.nlm.nih.gov/pubmed/35269409 http://dx.doi.org/10.3390/cells11050787

Ejemplares similares

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection
por: Qin, Wanhai, et al.
Publicado: (2021)

Role of Myeloid Tet Methylcytosine Dioxygenase 2 in Pulmonary and Peritoneal Inflammation Induced by Lipopolysaccharide and Peritonitis Induced by Escherichia coli
por: Qin, Wanhai, et al.
Publicado: (2021)

Myeloid DNA methyltransferase3b deficiency aggravates pulmonary fibrosis by enhancing profibrotic macrophage activation
por: Qin, Wanhai, et al.
Publicado: (2022)

Myeloid miR-155 plays a limited role in antibacterial defense during Klebsiella-derived pneumosepsis and is dispensable for lipopolysaccharide- or Klebsiella-induced inflammation in mice
por: Qin, Wanhai, et al.
Publicado: (2023)

The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection
por: Qin, Wanhai, et al.
Publicado: (2021)

Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia
por: Brands, Xanthe, et al.
Publicado: (2020)

Corrigendum: Concurrent Immune Suppression and Hyperinflammation in Patients With Community-Acquired Pneumonia
por: Brands, Xanthe, et al.
Publicado: (2020)

Transcriptional changes in alveolar macrophages from adults with asthma after allergen challenge
por: Yang, Jack, et al.
Publicado: (2021)

Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis
por: Ding, Chao, et al.
Publicado: (2019)

Role of tissue factor in the procoagulant and antibacterial effects of human adipose-derived mesenchymal stem cells during pneumosepsis in mice
por: Perlee, Desirée, et al.
Publicado: (2019)

Rectal microbiota are coupled with altered cytokine production capacity following community-acquired pneumonia hospitalization
por: Kullberg, Robert F.J., et al.
Publicado: (2022)

Hematopoietic but Not Endothelial Cell MyD88 Contributes to Host Defense during Gram-negative Pneumonia Derived Sepsis
por: van Lieshout, Miriam H. P., et al.
Publicado: (2014)

Impact of the factor V Leiden mutation on the outcome of pneumococcal pneumonia: a controlled laboratory study
por: Schouten, Marcel, et al.
Publicado: (2010)

Protease-activated receptor-1 impairs host defense in murine pneumococcal pneumonia: a controlled laboratory study
por: Schouten, Marcel, et al.
Publicado: (2012)

Prekallikrein inhibits innate immune signaling in the lung and impairs host defense during pneumosepsis in mice
por: Ding, Chao, et al.
Publicado: (2019)

Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antibacterial effects in murine pneumococcal pneumonia
por: Boogaard, F van den, et al.
Publicado: (2009)

C3a signaling is not involved in eosinophil migration during experimental allergic lung inflammation in mice
por: Yang, Jack, et al.
Publicado: (2019)

An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration
por: Brands, Xanthe, et al.
Publicado: (2021)

Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia
por: Schuurman, Alex R., et al.
Publicado: (2023)

Role of Tumor Necrosis Factor-α in the Human Systemic Endotoxin-Induced Transcriptome
por: Scicluna, Brendon P., et al.
Publicado: (2013)

Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients
por: Brands, Xanthe, et al.
Publicado: (2022)

Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis
por: Achouiti, Ahmed, et al.
Publicado: (2012)

Genetic signature related to heme-hemoglobin metabolism pathway in sepsis secondary to pneumonia
por: Leite, Giuseppe Gianini Figuerêido, et al.
Publicado: (2019)

Rectal bacteriome and virome signatures and clinical outcomes in community-acquired pneumonia: An exploratory study
por: Kullberg, Robert F.J., et al.
Publicado: (2021)

Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae-Evoked Pneumosepsis in Mice
por: Meijer, Mariska T., et al.
Publicado: (2021)

Interleukin-27: a potential new sepsis biomarker exposed through genome-wide transcriptional profiling
por: Scicluna, Brendon P, et al.
Publicado: (2012)

Inhalation of β2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract
por: Maris, Nico A, et al.
Publicado: (2006)

HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis
por: Matsumoto, Hisatake, et al.
Publicado: (2021)

Human Adipose‐Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae
por: Perlee, Desiree, et al.
Publicado: (2019)

The Long Non-Coding Antisense RNA JHDM1D-AS1 Regulates Inflammatory Responses in Human Monocytes
por: Malmström, Erik, et al.
Publicado: (2022)

Bruton’s Tyrosine Kinase-Mediated Signaling in Myeloid Cells Is Required for Protective Innate Immunity During Pneumococcal Pneumonia
por: de Porto, Alexander P., et al.
Publicado: (2021)

Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae
por: Liu, Zhe, et al.
Publicado: (2022)

Tenascin C Has a Modest Protective Effect on Acute Lung Pathology during Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia in Mice
por: Meijer, Mariska T., et al.
Publicado: (2021)

Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia
por: Achouiti, Ahmed, et al.
Publicado: (2016)

Association of Hyperferritinemia With Distinct Host Response Aberrations in Patients With Community-Acquired Pneumonia
por: Brands, Xanthe, et al.
Publicado: (2022)

The host response in different aetiologies of community-acquired pneumonia
por: Schuurman, Alex R., et al.
Publicado: (2022)

Interleukin‐33 improves local immunity during Gram‐negative pneumonia by a combined effect on neutrophils and inflammatory monocytes
por: Ramirez‐Moral, Ivan, et al.
Publicado: (2021)

Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia
por: Hommes, Tijmen J., et al.
Publicado: (2015)

Bacterial and Viral Respiratory Tract Microbiota and Host Characteristics in Adults With Lower Respiratory Tract Infections: A Case-Control Study
por: Haak, Bastiaan W, et al.
Publicado: (2021)

Limited Anti-Inflammatory Role for Interleukin-1 Receptor Like 1 (ST2) in the Host Response to Murine Postinfluenza Pneumococcal Pneumonia
por: Blok, Dana C., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3v08qcfo7ed7q4jafrbrp8snre