Sesquiterpene Lactones Attenuate Paclitaxel Resistance Via Inhibiting MALAT1/STAT3/ FUT4 Axis and P-Glycoprotein Transporters in Lung Cancer Cells

Paclitaxel resistance is a challenging factor in chemotherapy resulting in poor prognosis and cancer recurrence. Signal transducer and activator of transcription factor 3 (STAT3), a key transcription factor, performs a critical role in cancer development, cell survival and chemoresistance, while its...

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Detalles Bibliográficos
Autores principales: Ding, Yaming, Zhen, Zhang, Nisar, Muhammad Azhar, Ali, Farman, Din, Riaz Ud, Khan, Muhammad, Mughal, Tafail Akbar, Alam, Gulzar, Liu, Linlin, Saleem, Muhammad Zubair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8909900/
https://www.ncbi.nlm.nih.gov/pubmed/35281907
http://dx.doi.org/10.3389/fphar.2022.795613

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