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Senescent CD4(+)CD28(−) T Lymphocytes as a Potential Driver of Th17/Treg Imbalance and Alveolar Bone Resorption during Periodontitis

Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-inflammatory bias, which contributes to the chronicity of inflammation. During chronic inflammatory diseases, infiltrating CD4(+) T lymphocytes can undergo cellular senescence and arrest the surface expression of C...

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Detalles Bibliográficos
Autores principales:	González-Osuna, Luis, Sierra-Cristancho, Alfredo, Cafferata, Emilio A., Melgar-Rodríguez, Samanta, Rojas, Carolina, Carvajal, Paola, Cortez, Cristian, Vernal, Rolando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910032/ https://www.ncbi.nlm.nih.gov/pubmed/35269683 http://dx.doi.org/10.3390/ijms23052543

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