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Atherosclerosis in HIV Patients: What Do We Know so Far?
For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drug...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910073/ https://www.ncbi.nlm.nih.gov/pubmed/35269645 http://dx.doi.org/10.3390/ijms23052504 |
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author | Poznyak, Anastasia V. Bezsonov, Evgeny E. Borisov, Evgeny E. Grechko, Andrey V. Kartuesov, Andrey G. Orekhov, Alexander N. |
author_facet | Poznyak, Anastasia V. Bezsonov, Evgeny E. Borisov, Evgeny E. Grechko, Andrey V. Kartuesov, Andrey G. Orekhov, Alexander N. |
author_sort | Poznyak, Anastasia V. |
collection | PubMed |
description | For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drugs makes it possible to reduce the risk of transmission of the virus to almost zero. Atherosclerosis is another serious pathology that leads to severe health problems, including disability and, often, the death of the patient. An effective treatment for atherosclerosis has not yet been developed. Both types of immune response, innate and adaptive, are important components of the pathogenesis of this disease. In this regard, the peculiarities of the development of atherosclerosis in HIV carriers are of particular scientific interest. In this review, we have tried to summarize the data on atherosclerosis and its development in HIV carriers. We also looked at the classic therapeutic methods and their features concerning the concomitant diagnosis. |
format | Online Article Text |
id | pubmed-8910073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-89100732022-03-11 Atherosclerosis in HIV Patients: What Do We Know so Far? Poznyak, Anastasia V. Bezsonov, Evgeny E. Borisov, Evgeny E. Grechko, Andrey V. Kartuesov, Andrey G. Orekhov, Alexander N. Int J Mol Sci Review For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drugs makes it possible to reduce the risk of transmission of the virus to almost zero. Atherosclerosis is another serious pathology that leads to severe health problems, including disability and, often, the death of the patient. An effective treatment for atherosclerosis has not yet been developed. Both types of immune response, innate and adaptive, are important components of the pathogenesis of this disease. In this regard, the peculiarities of the development of atherosclerosis in HIV carriers are of particular scientific interest. In this review, we have tried to summarize the data on atherosclerosis and its development in HIV carriers. We also looked at the classic therapeutic methods and their features concerning the concomitant diagnosis. MDPI 2022-02-24 /pmc/articles/PMC8910073/ /pubmed/35269645 http://dx.doi.org/10.3390/ijms23052504 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Poznyak, Anastasia V. Bezsonov, Evgeny E. Borisov, Evgeny E. Grechko, Andrey V. Kartuesov, Andrey G. Orekhov, Alexander N. Atherosclerosis in HIV Patients: What Do We Know so Far? |
title | Atherosclerosis in HIV Patients: What Do We Know so Far? |
title_full | Atherosclerosis in HIV Patients: What Do We Know so Far? |
title_fullStr | Atherosclerosis in HIV Patients: What Do We Know so Far? |
title_full_unstemmed | Atherosclerosis in HIV Patients: What Do We Know so Far? |
title_short | Atherosclerosis in HIV Patients: What Do We Know so Far? |
title_sort | atherosclerosis in hiv patients: what do we know so far? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910073/ https://www.ncbi.nlm.nih.gov/pubmed/35269645 http://dx.doi.org/10.3390/ijms23052504 |
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