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Atherosclerosis in HIV Patients: What Do We Know so Far?

For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drug...

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Autores principales: Poznyak, Anastasia V., Bezsonov, Evgeny E., Borisov, Evgeny E., Grechko, Andrey V., Kartuesov, Andrey G., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910073/
https://www.ncbi.nlm.nih.gov/pubmed/35269645
http://dx.doi.org/10.3390/ijms23052504
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author Poznyak, Anastasia V.
Bezsonov, Evgeny E.
Borisov, Evgeny E.
Grechko, Andrey V.
Kartuesov, Andrey G.
Orekhov, Alexander N.
author_facet Poznyak, Anastasia V.
Bezsonov, Evgeny E.
Borisov, Evgeny E.
Grechko, Andrey V.
Kartuesov, Andrey G.
Orekhov, Alexander N.
author_sort Poznyak, Anastasia V.
collection PubMed
description For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drugs makes it possible to reduce the risk of transmission of the virus to almost zero. Atherosclerosis is another serious pathology that leads to severe health problems, including disability and, often, the death of the patient. An effective treatment for atherosclerosis has not yet been developed. Both types of immune response, innate and adaptive, are important components of the pathogenesis of this disease. In this regard, the peculiarities of the development of atherosclerosis in HIV carriers are of particular scientific interest. In this review, we have tried to summarize the data on atherosclerosis and its development in HIV carriers. We also looked at the classic therapeutic methods and their features concerning the concomitant diagnosis.
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spelling pubmed-89100732022-03-11 Atherosclerosis in HIV Patients: What Do We Know so Far? Poznyak, Anastasia V. Bezsonov, Evgeny E. Borisov, Evgeny E. Grechko, Andrey V. Kartuesov, Andrey G. Orekhov, Alexander N. Int J Mol Sci Review For the past several decades, humanity has been dealing with HIV. This disease is one of the biggest global health problems. Fortunately, modern antiretroviral therapy allows patients to manage the disease, improving their quality of life and their life expectancy. In addition, the use of these drugs makes it possible to reduce the risk of transmission of the virus to almost zero. Atherosclerosis is another serious pathology that leads to severe health problems, including disability and, often, the death of the patient. An effective treatment for atherosclerosis has not yet been developed. Both types of immune response, innate and adaptive, are important components of the pathogenesis of this disease. In this regard, the peculiarities of the development of atherosclerosis in HIV carriers are of particular scientific interest. In this review, we have tried to summarize the data on atherosclerosis and its development in HIV carriers. We also looked at the classic therapeutic methods and their features concerning the concomitant diagnosis. MDPI 2022-02-24 /pmc/articles/PMC8910073/ /pubmed/35269645 http://dx.doi.org/10.3390/ijms23052504 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Poznyak, Anastasia V.
Bezsonov, Evgeny E.
Borisov, Evgeny E.
Grechko, Andrey V.
Kartuesov, Andrey G.
Orekhov, Alexander N.
Atherosclerosis in HIV Patients: What Do We Know so Far?
title Atherosclerosis in HIV Patients: What Do We Know so Far?
title_full Atherosclerosis in HIV Patients: What Do We Know so Far?
title_fullStr Atherosclerosis in HIV Patients: What Do We Know so Far?
title_full_unstemmed Atherosclerosis in HIV Patients: What Do We Know so Far?
title_short Atherosclerosis in HIV Patients: What Do We Know so Far?
title_sort atherosclerosis in hiv patients: what do we know so far?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910073/
https://www.ncbi.nlm.nih.gov/pubmed/35269645
http://dx.doi.org/10.3390/ijms23052504
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