Deficiency in Retinal TGFβ Signaling Aggravates Neurodegeneration by Modulating Pro-Apoptotic and MAP Kinase Pathways

Transforming growth factor β (TGFβ) signaling has manifold functions such as regulation of cell growth, differentiation, migration, and apoptosis. Moreover, there is increasing evidence that it also acts in a neuroprotective manner. We recently showed that TGFβ receptor type 2 (Tgfbr2) is upregulate...

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Detalles Bibliográficos
Autores principales: Bielmeier, Christina B., Schmitt, Sabrina I., Kleefeldt, Nikolai, Boneva, Stefaniya K., Schlecht, Anja, Vallon, Mario, Tamm, Ernst R., Hillenkamp, Jost, Ergün, Süleyman, Neueder, Andreas, Braunger, Barbara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8910086/
https://www.ncbi.nlm.nih.gov/pubmed/35269767
http://dx.doi.org/10.3390/ijms23052626

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